The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification
Abstract Background and aims The increasing prevalence of metabolic and cardiovascular diseases poses a significant challenge to global healthcare systems. Regular physical activity (PA) is recognized for its positive impact on cardiovascular risk factors. This study aimed to investigate the relatio...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2023-10-01
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| Series: | Journal of Translational Medicine |
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| Online Access: | https://doi.org/10.1186/s12967-023-04566-w |
| _version_ | 1827633332291108864 |
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| author | Chang Sheng Weihua Huang Wei Wang Guoqiang Lin Mingmei Liao Pu Yang |
| author_facet | Chang Sheng Weihua Huang Wei Wang Guoqiang Lin Mingmei Liao Pu Yang |
| author_sort | Chang Sheng |
| collection | DOAJ |
| description | Abstract Background and aims The increasing prevalence of metabolic and cardiovascular diseases poses a significant challenge to global healthcare systems. Regular physical activity (PA) is recognized for its positive impact on cardiovascular risk factors. This study aimed to investigate the relationship between moderate-to-vigorous physical activity (MVPA), sedentary behavior (SB), and abdominal aortic calcification (AAC) using data from the National Health and Nutrition Examination Survey (NHANES). Methods The study used data from NHANES participants aged 40 and above during the 2013–2014 cycle. AAC scores were assessed using the Kauppila scoring system, and MVPA and SB were self-reported. Sociodemographic variables were considered, and multivariable linear regression models were used to analyze associations between MVPA, SB, and AAC scores. Subgroup analyses were conducted based on age, sex, BMI, hypertension, and diabetes. Results The study included 2843 participants. AAC prevalence was higher in older age groups, smokers, and those with diabetes or hypertension. Lower socioeconomic status was associated with higher AAC prevalence. Individuals engaged in any level of MVPA exhibited lower AAC rates compared to inactive individuals. Not engaging in occupational MVPA (β = 0.46, 95% confidence interval = 0.24‒0.67, p < .001) and prolonged SB (β = 0.28, 95% confidence interval = 0.04‒0.52, p = .023) were associated with higher AAC scores. However, no significant associations were found for transportation and leisure time MVPA. Subgroup analysis revealed age and hypertension as effect modifiers in the MVPA-AAC relationship. Conclusions This study highlights the potential benefits of engaging in occupational MVPA and reducing SB in mitigating AAC scores, particularly among older individuals and those with hypertension. |
| first_indexed | 2024-03-09T14:58:04Z |
| format | Article |
| id | doaj.art-58f473fbe80b498b9a121f1edbb75f92 |
| institution | Directory Open Access Journal |
| issn | 1479-5876 |
| language | English |
| last_indexed | 2024-03-09T14:58:04Z |
| publishDate | 2023-10-01 |
| publisher | BMC |
| record_format | Article |
| series | Journal of Translational Medicine |
| spelling | doaj.art-58f473fbe80b498b9a121f1edbb75f922023-11-26T14:04:37ZengBMCJournal of Translational Medicine1479-58762023-10-0121111210.1186/s12967-023-04566-wThe association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcificationChang Sheng0Weihua Huang1Wei Wang2Guoqiang Lin3Mingmei Liao4Pu Yang5Department of Vascular Surgery, Xiangya Hospital, Central South UniversityDepartment of Clinical Pharmacology, Hunan Key Laboratory of Pharmacogenetics, Xiangya Hospital, Central South UniversityDepartment of Vascular Surgery, Xiangya Hospital, Central South UniversityNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South UniversityNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Central South UniversityDepartment of Vascular Surgery, Xiangya Hospital, Central South UniversityAbstract Background and aims The increasing prevalence of metabolic and cardiovascular diseases poses a significant challenge to global healthcare systems. Regular physical activity (PA) is recognized for its positive impact on cardiovascular risk factors. This study aimed to investigate the relationship between moderate-to-vigorous physical activity (MVPA), sedentary behavior (SB), and abdominal aortic calcification (AAC) using data from the National Health and Nutrition Examination Survey (NHANES). Methods The study used data from NHANES participants aged 40 and above during the 2013–2014 cycle. AAC scores were assessed using the Kauppila scoring system, and MVPA and SB were self-reported. Sociodemographic variables were considered, and multivariable linear regression models were used to analyze associations between MVPA, SB, and AAC scores. Subgroup analyses were conducted based on age, sex, BMI, hypertension, and diabetes. Results The study included 2843 participants. AAC prevalence was higher in older age groups, smokers, and those with diabetes or hypertension. Lower socioeconomic status was associated with higher AAC prevalence. Individuals engaged in any level of MVPA exhibited lower AAC rates compared to inactive individuals. Not engaging in occupational MVPA (β = 0.46, 95% confidence interval = 0.24‒0.67, p < .001) and prolonged SB (β = 0.28, 95% confidence interval = 0.04‒0.52, p = .023) were associated with higher AAC scores. However, no significant associations were found for transportation and leisure time MVPA. Subgroup analysis revealed age and hypertension as effect modifiers in the MVPA-AAC relationship. Conclusions This study highlights the potential benefits of engaging in occupational MVPA and reducing SB in mitigating AAC scores, particularly among older individuals and those with hypertension.https://doi.org/10.1186/s12967-023-04566-wPhysical activitySedentary behaviorAbdominal aortic calcificationCardiovascular risk factorsNHANES |
| spellingShingle | Chang Sheng Weihua Huang Wei Wang Guoqiang Lin Mingmei Liao Pu Yang The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification Journal of Translational Medicine Physical activity Sedentary behavior Abdominal aortic calcification Cardiovascular risk factors NHANES |
| title | The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification |
| title_full | The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification |
| title_fullStr | The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification |
| title_full_unstemmed | The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification |
| title_short | The association of moderate-to-vigorous physical activity and sedentary behaviour with abdominal aortic calcification |
| title_sort | association of moderate to vigorous physical activity and sedentary behaviour with abdominal aortic calcification |
| topic | Physical activity Sedentary behavior Abdominal aortic calcification Cardiovascular risk factors NHANES |
| url | https://doi.org/10.1186/s12967-023-04566-w |
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