In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review
Boron nitride nanotubes (BNNTs) are an exciting class of nanomaterials due to their unique chemical and physical characteristics. In recent decades, BNNTs have gained huge attention in research and development for various applications, including as nano-fillers for composites, semiconductor devices,...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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MDPI AG
2022-06-01
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| Series: | Nanomaterials |
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| Online Access: | https://www.mdpi.com/2079-4991/12/12/2069 |
| _version_ | 1797483799430299648 |
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| author | Akesh Babu Kakarla Ing Kong |
| author_facet | Akesh Babu Kakarla Ing Kong |
| author_sort | Akesh Babu Kakarla |
| collection | DOAJ |
| description | Boron nitride nanotubes (BNNTs) are an exciting class of nanomaterials due to their unique chemical and physical characteristics. In recent decades, BNNTs have gained huge attention in research and development for various applications, including as nano-fillers for composites, semiconductor devices, hydrogen storage, and as an emerging material in biomedical and tissue engineering applications. However, the toxicity of BNNTs is not clear, and the biocompatibility is not proven yet. In this review, the role of BNNTs in biocompatibility studies is assessed in terms of their characteristics: cell viability, proliferation, therapeutic outcomes, and genotoxicity, which are vital elements for their prospective use in biomedical applications. A systematic review was conducted utilising the databases Scopus and Web of Science (WOS) (2008–2022). Additional findings were discovered manually by snowballing the reference lists of appropriate reviews. Only English-language articles were included. Finally, the significant analysis and discussion of the chosen articles are presented. |
| first_indexed | 2024-03-09T22:52:16Z |
| format | Article |
| id | doaj.art-58faa2f2dbd741c69aae5cac5a303e97 |
| institution | Directory Open Access Journal |
| issn | 2079-4991 |
| language | English |
| last_indexed | 2024-03-09T22:52:16Z |
| publishDate | 2022-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Nanomaterials |
| spelling | doaj.art-58faa2f2dbd741c69aae5cac5a303e972023-11-23T18:17:01ZengMDPI AGNanomaterials2079-49912022-06-011212206910.3390/nano12122069In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic ReviewAkesh Babu Kakarla0Ing Kong1School of Computing, Engineering and Mathematical Sciences, La Trobe University, Bendigo, VIC 3552, AustraliaSchool of Computing, Engineering and Mathematical Sciences, La Trobe University, Bendigo, VIC 3552, AustraliaBoron nitride nanotubes (BNNTs) are an exciting class of nanomaterials due to their unique chemical and physical characteristics. In recent decades, BNNTs have gained huge attention in research and development for various applications, including as nano-fillers for composites, semiconductor devices, hydrogen storage, and as an emerging material in biomedical and tissue engineering applications. However, the toxicity of BNNTs is not clear, and the biocompatibility is not proven yet. In this review, the role of BNNTs in biocompatibility studies is assessed in terms of their characteristics: cell viability, proliferation, therapeutic outcomes, and genotoxicity, which are vital elements for their prospective use in biomedical applications. A systematic review was conducted utilising the databases Scopus and Web of Science (WOS) (2008–2022). Additional findings were discovered manually by snowballing the reference lists of appropriate reviews. Only English-language articles were included. Finally, the significant analysis and discussion of the chosen articles are presented.https://www.mdpi.com/2079-4991/12/12/2069boron nitride nanotubestoxicitycytotoxicitybiocompatibilitybiomedicaltissue engineering |
| spellingShingle | Akesh Babu Kakarla Ing Kong In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review Nanomaterials boron nitride nanotubes toxicity cytotoxicity biocompatibility biomedical tissue engineering |
| title | In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review |
| title_full | In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review |
| title_fullStr | In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review |
| title_full_unstemmed | In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review |
| title_short | In Vitro and In Vivo Cytotoxicity of Boron Nitride Nanotubes: A Systematic Review |
| title_sort | in vitro and in vivo cytotoxicity of boron nitride nanotubes a systematic review |
| topic | boron nitride nanotubes toxicity cytotoxicity biocompatibility biomedical tissue engineering |
| url | https://www.mdpi.com/2079-4991/12/12/2069 |
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