Simultaneous Maturation of Single Chain Antibody Stability and Affinity by CHO Cell Display

Simultaneous Maturation of Single Chain Antibody Stability and Affinity by CHO Cell Display

Antibody stability and affinity are two important features of its applications in therapy and diagnosis. Antibody display technologies such as yeast and bacterial displays have been successfully used for improving both affinity and stability. Although mammalian cell display has also been utilized fo...

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Bibliographic Details
Main Authors: Ruiqi Luo, Baole Qu, Lili An, Yun Zhao, Yang Cao, Peng Ren, Haiying Hang
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Bioengineering
Subjects:
stability
affinity maturation
mammalian cell display
thermo-resistant CHO cells
Online Access:https://www.mdpi.com/2306-5354/9/8/360

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