Quinazolin-4-one/3-cyanopyridin-2-one Hybrids as Dual Inhibitors of EGFR and BRAF<sup>V600E</sup>: Design, Synthesis, and Antiproliferative Activity
A novel series of hybrid compounds comprising quinazolin-4-one and 3-cyanopyridin-2-one structures has been developed, with dual inhibitory actions on both EGFR and BRAF<sup>V600E</sup>. These hybrid compounds were tested in vitro against four different cancer cell lines. Compounds <b...
| Հիմնական հեղինակներ: | , , , , , , , |
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| Ձևաչափ: | Հոդված |
| Լեզու: | English |
| Հրապարակվել է: |
MDPI AG
2023-10-01
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| Շարք: | Pharmaceuticals |
| Խորագրեր: | |
| Առցանց հասանելիություն: | https://www.mdpi.com/1424-8247/16/11/1522 |