In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass

In-stent thrombosis (IST) is a rare yet dangerous complication that may occur despite optimized coronary intervention in the cardiac catheterization laboratory. This is a case of an 81-year-old man who presented with ST-elevation myocardial infarction. Right coronary artery (RCA) occlusion was suspe...

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Main Authors: Nathan Burke, Tawanna Charlton, Hussam Hawamdeh, Ki Park
Format: Article
Language:English
Published: Compuscript Ltd 2020-10-01
Series:Cardiovascular Innovations and Applications
Online Access:https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2019.0589
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author Nathan Burke
Tawanna Charlton
Hussam Hawamdeh
Ki Park
author_facet Nathan Burke
Tawanna Charlton
Hussam Hawamdeh
Ki Park
author_sort Nathan Burke
collection DOAJ
description In-stent thrombosis (IST) is a rare yet dangerous complication that may occur despite optimized coronary intervention in the cardiac catheterization laboratory. This is a case of an 81-year-old man who presented with ST-elevation myocardial infarction. Right coronary artery (RCA) occlusion was suspected. RCA angiography and percutaneous coronary intervention were performed. Complicated left coronary artery disease was subsequently discovered. Per cardiothoracic surgeon request, the patient was transitioned from ticagrelor to clopidogrel therapy in preparation for coronary artery bypass grafting. The patient experienced IST the day before surgery while receiving clopidogrel. We examine this case, which highlights the complexity of antiplatelet therapy choice and the role of genetic testing in evaluation of IST risk.
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spelling doaj.art-58ffbe6eea2e43e18d43780a2194d0ec2023-06-28T13:57:23ZengCompuscript LtdCardiovascular Innovations and Applications2009-86182009-87822020-10-015213910.15212/CVIA.2019.0589In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary BypassNathan BurkeTawanna CharltonHussam HawamdehKi ParkIn-stent thrombosis (IST) is a rare yet dangerous complication that may occur despite optimized coronary intervention in the cardiac catheterization laboratory. This is a case of an 81-year-old man who presented with ST-elevation myocardial infarction. Right coronary artery (RCA) occlusion was suspected. RCA angiography and percutaneous coronary intervention were performed. Complicated left coronary artery disease was subsequently discovered. Per cardiothoracic surgeon request, the patient was transitioned from ticagrelor to clopidogrel therapy in preparation for coronary artery bypass grafting. The patient experienced IST the day before surgery while receiving clopidogrel. We examine this case, which highlights the complexity of antiplatelet therapy choice and the role of genetic testing in evaluation of IST risk.https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2019.0589
spellingShingle Nathan Burke
Tawanna Charlton
Hussam Hawamdeh
Ki Park
In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
Cardiovascular Innovations and Applications
title In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_full In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_fullStr In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_full_unstemmed In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_short In-Stent Thrombosis after Antiplatelet Therapy Conversion while Awaiting Coronary Bypass
title_sort in stent thrombosis after antiplatelet therapy conversion while awaiting coronary bypass
url https://www.scienceopen.com/hosted-document?doi=10.15212/CVIA.2019.0589
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AT tawannacharlton instentthrombosisafterantiplatelettherapyconversionwhileawaitingcoronarybypass
AT hussamhawamdeh instentthrombosisafterantiplatelettherapyconversionwhileawaitingcoronarybypass
AT kipark instentthrombosisafterantiplatelettherapyconversionwhileawaitingcoronarybypass