Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir
Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunolog...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2021-01-01
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| Series: | IDCases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214250921002870 |
| _version_ | 1819004555648565248 |
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| author | Caterina Foti Elvira Favoino Maria Scarasciulli Anna Maria Colacicco Hamidreza Jahantigh Angela Stufano Piero Lovreglio Paola Mascia Chiara Barlusconi Federico Perosa Paolo Romita Agata Calvario |
| author_facet | Caterina Foti Elvira Favoino Maria Scarasciulli Anna Maria Colacicco Hamidreza Jahantigh Angela Stufano Piero Lovreglio Paola Mascia Chiara Barlusconi Federico Perosa Paolo Romita Agata Calvario |
| author_sort | Caterina Foti |
| collection | DOAJ |
| description | Among different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunologic response. Our report evaluated EBV-specific T cell responses by IFN- γ ELISPOT assay, which revealed defective EBV specific immunological response. |
| first_indexed | 2024-12-20T23:38:46Z |
| format | Article |
| id | doaj.art-590131e0b4464b74b899bbfe4ad66ccb |
| institution | Directory Open Access Journal |
| issn | 2214-2509 |
| language | English |
| last_indexed | 2024-12-20T23:38:46Z |
| publishDate | 2021-01-01 |
| publisher | Elsevier |
| record_format | Article |
| series | IDCases |
| spelling | doaj.art-590131e0b4464b74b899bbfe4ad66ccb2022-12-21T19:23:09ZengElsevierIDCases2214-25092021-01-0126e01331Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with ValaciclovirCaterina Foti0Elvira Favoino1Maria Scarasciulli2Anna Maria Colacicco3Hamidreza Jahantigh4Angela Stufano5Piero Lovreglio6Paola Mascia7Chiara Barlusconi8Federico Perosa9Paolo Romita10Agata Calvario11Department of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari “Aldo Moro”, Bari, Italy; Corresponding author.Department of Biomedical Science and Human Oncology (DIMO), Rheumatic and Systemic Autoimmune Diseases Unit, University of Bari Medical School, Bari, ItalyMicrobiology and Virology Unit - Interdisciplinary Department of Medicine (DIM) - University of Bari ''Aldo Moro''- AOU Policlinico Bari, ItalyMicrobiology and Virology Unit - Interdisciplinary Department of Medicine (DIM) - University of Bari ''Aldo Moro''- AOU Policlinico Bari, ItalyInterdisciplinary Department of Medicine, University of Bari ''Aldo Moro'', 70124 Bari, ItalyInterdisciplinary Department of Medicine, University of Bari ''Aldo Moro'', 70124 Bari, ItalyInterdisciplinary Department of Medicine, University of Bari ''Aldo Moro'', 70124 Bari, ItalyDepartment of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari “Aldo Moro”, Bari, ItalyDepartment of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari “Aldo Moro”, Bari, ItalyDepartment of Biomedical Science and Human Oncology (DIMO), Rheumatic and Systemic Autoimmune Diseases Unit, University of Bari Medical School, Bari, ItalyDepartment of Biomedical Science and Human Oncology, Dermatological Clinic, University of Bari “Aldo Moro”, Bari, ItalyMicrobiology and Virology Unit - Interdisciplinary Department of Medicine (DIM) - University of Bari ''Aldo Moro''- AOU Policlinico Bari, ItalyAmong different pathogens, opportunistic viral infection caused by EBV is particularly relevant. This gammaherpesvirus, belonging to the Herpesviridae family, may complicate the disease course in different clinical settings by inducing pathological EBV pictures in patients with a defective immunologic response. Our report evaluated EBV-specific T cell responses by IFN- γ ELISPOT assay, which revealed defective EBV specific immunological response.http://www.sciencedirect.com/science/article/pii/S2214250921002870 |
| spellingShingle | Caterina Foti Elvira Favoino Maria Scarasciulli Anna Maria Colacicco Hamidreza Jahantigh Angela Stufano Piero Lovreglio Paola Mascia Chiara Barlusconi Federico Perosa Paolo Romita Agata Calvario Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir IDCases |
| title | Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir |
| title_full | Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir |
| title_fullStr | Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir |
| title_full_unstemmed | Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir |
| title_short | Chronic-Relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced EBV-specific T cell response using enzyme-linked immunospot (ELISPOT) assay successfully treated with Valaciclovir |
| title_sort | chronic relapsing cutaneous leukocytoclastic vasculitis in a young patient with reduced ebv specific t cell response using enzyme linked immunospot elispot assay successfully treated with valaciclovir |
| url | http://www.sciencedirect.com/science/article/pii/S2214250921002870 |
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