Instrumentation in Diffuse Optical Imaging

Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence and a number of other new imaging methods. These methods of diffuse optical imaging have dive...

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Main Author: Xiaofeng Zhang
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Photonics
Subjects:
Online Access:http://www.mdpi.com/2304-6732/1/1/9
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author Xiaofeng Zhang
author_facet Xiaofeng Zhang
author_sort Xiaofeng Zhang
collection DOAJ
description Diffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument configurations, but share the same core physical principle: light propagation in highly diffusive media, i.e., biological tissue. In this review, the author summarizes the latest development in instrumentation and methodology available to diffuse optical imaging in terms of system architecture, light source, photo-detection, spectral separation, signal modulation and, lastly, imaging contrast.
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spelling doaj.art-590163d68ebb419890ece04e790ea50d2022-12-22T03:41:24ZengMDPI AGPhotonics2304-67322014-03-011193210.3390/photonics1010009photonics1010009Instrumentation in Diffuse Optical ImagingXiaofeng Zhang0Department of Radiology, Duke University Medical Center, DUMC 3808, Durham, NC 27710, USADiffuse optical imaging is highly versatile and has a very broad range of applications in biology and medicine. It covers diffuse optical tomography, fluorescence diffuse optical tomography, bioluminescence and a number of other new imaging methods. These methods of diffuse optical imaging have diversified instrument configurations, but share the same core physical principle: light propagation in highly diffusive media, i.e., biological tissue. In this review, the author summarizes the latest development in instrumentation and methodology available to diffuse optical imaging in terms of system architecture, light source, photo-detection, spectral separation, signal modulation and, lastly, imaging contrast.http://www.mdpi.com/2304-6732/1/1/9diffuse optical imaginginstrumentationfluorescencemolecular imagingbioluminescencetomographyclinicalpreclinical
spellingShingle Xiaofeng Zhang
Instrumentation in Diffuse Optical Imaging
Photonics
diffuse optical imaging
instrumentation
fluorescence
molecular imaging
bioluminescence
tomography
clinical
preclinical
title Instrumentation in Diffuse Optical Imaging
title_full Instrumentation in Diffuse Optical Imaging
title_fullStr Instrumentation in Diffuse Optical Imaging
title_full_unstemmed Instrumentation in Diffuse Optical Imaging
title_short Instrumentation in Diffuse Optical Imaging
title_sort instrumentation in diffuse optical imaging
topic diffuse optical imaging
instrumentation
fluorescence
molecular imaging
bioluminescence
tomography
clinical
preclinical
url http://www.mdpi.com/2304-6732/1/1/9
work_keys_str_mv AT xiaofengzhang instrumentationindiffuseopticalimaging