Evaluation of Two Chemoenzymatic Glycan Remodeling Approaches to Generate Site-Specific Antibody–Drug Conjugates

Fc-glycosite-specific antibody–drug conjugation represents a promising direction for the preparation of site-specific antibody–drug conjugates (ADCs). In the present research, we conducted a systemic evaluation of two endoglycosidase-catalyzed chemoenzymatic glycoengineering technologies to prepare...

Повний опис

Бібліографічні деталі
Автори: Qiang Yang, He Chen, Chong Ou, Zhihao Zheng, Xiao Zhang, Yunpeng Liu, Guanghui Zong, Lai-Xi Wang
Формат: Стаття
Мова:English
Опубліковано: MDPI AG 2023-11-01
Серія:Antibodies
Предмети:
Онлайн доступ:https://www.mdpi.com/2073-4468/12/4/71