Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components

Along with its uses in a wide range of sectors, NP toxicity research was one of the fastest-growing areas of research, so the growing commercial applications brought aluminum oxide nanoparticles under the purview of toxicologists. This study shows the toxicity of Aluminum oxide Nanoparticles on bloo...

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Main Authors: Tuqa Sabah, kareem Jawad, Nebras Essam
Format: Article
Language:English
Published: University of Technology, Baghdad 2023-03-01
Series:Journal of Applied Sciences and Nanotechnology
Subjects:
Online Access:https://jasn.uotechnology.edu.iq/article_22719_6027b71ddc533e8d2d57d0b91703df67.pdf
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author Tuqa Sabah
kareem Jawad
Nebras Essam
author_facet Tuqa Sabah
kareem Jawad
Nebras Essam
author_sort Tuqa Sabah
collection DOAJ
description Along with its uses in a wide range of sectors, NP toxicity research was one of the fastest-growing areas of research, so the growing commercial applications brought aluminum oxide nanoparticles under the purview of toxicologists. This study shows the toxicity of Aluminum oxide Nanoparticles on blood components prepared using the pulsed laser ablation (PLA) <em>Nd: YAG</em> laser method. We confirmed the synthesis of aluminum Oxide nanoparticles by measuring color absorbance, UV-vis, scanning electron microscope techniques (SEM), and FTIR as characterization of Aluminum oxide Nanoparticles. The complete blood count (CBC) was used in the study of the toxicity effect of these nanoparticles on human blood parameters <em>(in vitro</em>). The results of hematology parameter platelet (PLT); hemoglobin (HGB–Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) are compared with the control groups, our results show no significant differences in levels of platelet (PLT); hemoglobin (HGB –Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) between the test groups when compared with control groups. This result that there indicates no toxic effect of Aluminum oxide nanoparticles in the hematology parameter (<em>in vitro</em>). This work is done for the first time to investigate the non-toxicity effect of these Al<sub>2</sub>O<sub>3</sub> NPS on human blood parameters.
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spelling doaj.art-5906977c81ac466aae59e2d04926394f2023-03-13T22:30:50ZengUniversity of Technology, BaghdadJournal of Applied Sciences and Nanotechnology2788-68672023-03-013181710.53293/jasn.2022.4746.114222719Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood ComponentsTuqa Sabah0kareem Jawad1Nebras Essam2Department of Laser & Optoelectronics Engineering, University of Technology – IraqDepartment of Laser & Optoelectronics Engineering, University of Technology – IraqDepartment of Laser & Optoelectronics Engineering, University of Technology – IraqAlong with its uses in a wide range of sectors, NP toxicity research was one of the fastest-growing areas of research, so the growing commercial applications brought aluminum oxide nanoparticles under the purview of toxicologists. This study shows the toxicity of Aluminum oxide Nanoparticles on blood components prepared using the pulsed laser ablation (PLA) <em>Nd: YAG</em> laser method. We confirmed the synthesis of aluminum Oxide nanoparticles by measuring color absorbance, UV-vis, scanning electron microscope techniques (SEM), and FTIR as characterization of Aluminum oxide Nanoparticles. The complete blood count (CBC) was used in the study of the toxicity effect of these nanoparticles on human blood parameters <em>(in vitro</em>). The results of hematology parameter platelet (PLT); hemoglobin (HGB–Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) are compared with the control groups, our results show no significant differences in levels of platelet (PLT); hemoglobin (HGB –Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) between the test groups when compared with control groups. This result that there indicates no toxic effect of Aluminum oxide nanoparticles in the hematology parameter (<em>in vitro</em>). This work is done for the first time to investigate the non-toxicity effect of these Al<sub>2</sub>O<sub>3</sub> NPS on human blood parameters.https://jasn.uotechnology.edu.iq/article_22719_6027b71ddc533e8d2d57d0b91703df67.pdfaluminum oxide nanoparticlestoxicityblood cells
spellingShingle Tuqa Sabah
kareem Jawad
Nebras Essam
Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components
Journal of Applied Sciences and Nanotechnology
aluminum oxide nanoparticles
toxicity
blood cells
title Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components
title_full Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components
title_fullStr Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components
title_full_unstemmed Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components
title_short Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components
title_sort assessing the toxicity of aluminum oxide nanoparticles al2o3 nps prepared by laser ablation technique on blood components
topic aluminum oxide nanoparticles
toxicity
blood cells
url https://jasn.uotechnology.edu.iq/article_22719_6027b71ddc533e8d2d57d0b91703df67.pdf
work_keys_str_mv AT tuqasabah assessingthetoxicityofaluminumoxidenanoparticlesal2o3npspreparedbylaserablationtechniqueonbloodcomponents
AT kareemjawad assessingthetoxicityofaluminumoxidenanoparticlesal2o3npspreparedbylaserablationtechniqueonbloodcomponents
AT nebrasessam assessingthetoxicityofaluminumoxidenanoparticlesal2o3npspreparedbylaserablationtechniqueonbloodcomponents