Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components
Along with its uses in a wide range of sectors, NP toxicity research was one of the fastest-growing areas of research, so the growing commercial applications brought aluminum oxide nanoparticles under the purview of toxicologists. This study shows the toxicity of Aluminum oxide Nanoparticles on bloo...
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Format: | Article |
Language: | English |
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University of Technology, Baghdad
2023-03-01
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Series: | Journal of Applied Sciences and Nanotechnology |
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Online Access: | https://jasn.uotechnology.edu.iq/article_22719_6027b71ddc533e8d2d57d0b91703df67.pdf |
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author | Tuqa Sabah kareem Jawad Nebras Essam |
author_facet | Tuqa Sabah kareem Jawad Nebras Essam |
author_sort | Tuqa Sabah |
collection | DOAJ |
description | Along with its uses in a wide range of sectors, NP toxicity research was one of the fastest-growing areas of research, so the growing commercial applications brought aluminum oxide nanoparticles under the purview of toxicologists. This study shows the toxicity of Aluminum oxide Nanoparticles on blood components prepared using the pulsed laser ablation (PLA) <em>Nd: YAG</em> laser method. We confirmed the synthesis of aluminum Oxide nanoparticles by measuring color absorbance, UV-vis, scanning electron microscope techniques (SEM), and FTIR as characterization of Aluminum oxide Nanoparticles. The complete blood count (CBC) was used in the study of the toxicity effect of these nanoparticles on human blood parameters <em>(in vitro</em>). The results of hematology parameter platelet (PLT); hemoglobin (HGB–Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) are compared with the control groups, our results show no significant differences in levels of platelet (PLT); hemoglobin (HGB –Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) between the test groups when compared with control groups. This result that there indicates no toxic effect of Aluminum oxide nanoparticles in the hematology parameter (<em>in vitro</em>). This work is done for the first time to investigate the non-toxicity effect of these Al<sub>2</sub>O<sub>3</sub> NPS on human blood parameters. |
first_indexed | 2024-04-10T00:44:56Z |
format | Article |
id | doaj.art-5906977c81ac466aae59e2d04926394f |
institution | Directory Open Access Journal |
issn | 2788-6867 |
language | English |
last_indexed | 2024-04-10T00:44:56Z |
publishDate | 2023-03-01 |
publisher | University of Technology, Baghdad |
record_format | Article |
series | Journal of Applied Sciences and Nanotechnology |
spelling | doaj.art-5906977c81ac466aae59e2d04926394f2023-03-13T22:30:50ZengUniversity of Technology, BaghdadJournal of Applied Sciences and Nanotechnology2788-68672023-03-013181710.53293/jasn.2022.4746.114222719Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood ComponentsTuqa Sabah0kareem Jawad1Nebras Essam2Department of Laser & Optoelectronics Engineering, University of Technology – IraqDepartment of Laser & Optoelectronics Engineering, University of Technology – IraqDepartment of Laser & Optoelectronics Engineering, University of Technology – IraqAlong with its uses in a wide range of sectors, NP toxicity research was one of the fastest-growing areas of research, so the growing commercial applications brought aluminum oxide nanoparticles under the purview of toxicologists. This study shows the toxicity of Aluminum oxide Nanoparticles on blood components prepared using the pulsed laser ablation (PLA) <em>Nd: YAG</em> laser method. We confirmed the synthesis of aluminum Oxide nanoparticles by measuring color absorbance, UV-vis, scanning electron microscope techniques (SEM), and FTIR as characterization of Aluminum oxide Nanoparticles. The complete blood count (CBC) was used in the study of the toxicity effect of these nanoparticles on human blood parameters <em>(in vitro</em>). The results of hematology parameter platelet (PLT); hemoglobin (HGB–Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) are compared with the control groups, our results show no significant differences in levels of platelet (PLT); hemoglobin (HGB –Hb); red blood cell (RBCs); white blood cell (WBCs); Count type white blood cells) between the test groups when compared with control groups. This result that there indicates no toxic effect of Aluminum oxide nanoparticles in the hematology parameter (<em>in vitro</em>). This work is done for the first time to investigate the non-toxicity effect of these Al<sub>2</sub>O<sub>3</sub> NPS on human blood parameters.https://jasn.uotechnology.edu.iq/article_22719_6027b71ddc533e8d2d57d0b91703df67.pdfaluminum oxide nanoparticlestoxicityblood cells |
spellingShingle | Tuqa Sabah kareem Jawad Nebras Essam Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components Journal of Applied Sciences and Nanotechnology aluminum oxide nanoparticles toxicity blood cells |
title | Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components |
title_full | Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components |
title_fullStr | Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components |
title_full_unstemmed | Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components |
title_short | Assessing the Toxicity of Aluminum Oxide Nanoparticles (Al2O3 NPS) Prepared by Laser Ablation Technique on Blood Components |
title_sort | assessing the toxicity of aluminum oxide nanoparticles al2o3 nps prepared by laser ablation technique on blood components |
topic | aluminum oxide nanoparticles toxicity blood cells |
url | https://jasn.uotechnology.edu.iq/article_22719_6027b71ddc533e8d2d57d0b91703df67.pdf |
work_keys_str_mv | AT tuqasabah assessingthetoxicityofaluminumoxidenanoparticlesal2o3npspreparedbylaserablationtechniqueonbloodcomponents AT kareemjawad assessingthetoxicityofaluminumoxidenanoparticlesal2o3npspreparedbylaserablationtechniqueonbloodcomponents AT nebrasessam assessingthetoxicityofaluminumoxidenanoparticlesal2o3npspreparedbylaserablationtechniqueonbloodcomponents |