COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults

Background: Concerns and misconceptions surrounding coronavirus disease 2019 (COVID-19) vaccines may account for vaccine hesitancy and low uptake. Aim: To determine prevalence of COVID-19 vaccine hesitancy, vaccine-related misconceptions, and predictors of vaccine hesitancy among South Africans. S...

Full description

Bibliographic Details
Main Authors: Tanuja N. Gengiah, Donavan C. Naidoo, Nomcebo Maduma, Saien Govender, Sherishka Dhindayal, Lara Lewis
Format: Article
Language:Afrikaans
Published: AOSIS 2024-02-01
Series:Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
Subjects:
Online Access:https://hsag.co.za/index.php/hsag/article/view/2468
_version_ 1797336103605239808
author Tanuja N. Gengiah
Donavan C. Naidoo
Nomcebo Maduma
Saien Govender
Sherishka Dhindayal
Lara Lewis
author_facet Tanuja N. Gengiah
Donavan C. Naidoo
Nomcebo Maduma
Saien Govender
Sherishka Dhindayal
Lara Lewis
author_sort Tanuja N. Gengiah
collection DOAJ
description Background: Concerns and misconceptions surrounding coronavirus disease 2019 (COVID-19) vaccines may account for vaccine hesitancy and low uptake. Aim: To determine prevalence of COVID-19 vaccine hesitancy, vaccine-related misconceptions, and predictors of vaccine hesitancy among South Africans. Setting: Community setting in five districts in KwaZulu- Natal province. Methods: Between August 20, 2021, and September 27, 2021, we conducted a cross-sectional survey, interviewing 300 unvaccinated adults amid the national vaccination campaign. Predictors of hesitancy were identified through multivariable logistic regression analysis. Results: Participants had a median age of 29 years (IQR: 23–39), 86.7% were Black African, 63.2% were male, 53.3% resided in rural communities, and 59.3% (95% CI: 53.8% – 64.9%) were classified as vaccine hesitant. The primary reason for not vaccinating was a lack of trust in the vaccine (62.1%). Factors associated with reduced vaccine hesitancy included age (participants aged 35–49 years: OR: 0.28, 95% CI: 0.18–0.64, p = 0.003; participants over 50 years: OR: 0.18, 95% CI: 0.07–0.47, p = 0.0004), previous COVID-19 infection (OR: 0.31, 95% CI: 0.11–0.87, p = 0.03), and receiving vaccine information from healthcare workers (OR: 0.32, 95% CI: 0.10–1.0, p = 0.05). Unemployed (OR: 2.14, 95% CI: 1.1–4.2, p = 0.03) and self-employed individuals (OR: 2.98, 95% CI: 1.27–7.02, p = 0.01) were more likely to be vaccine hesitant. Conclusion: COVID-19 vaccine hesitancy rates are high in KwaZulu-Natal. Uptake could be enhanced by healthcare workers leading information campaigns with messages targeting younger individuals, the unemployed, and the self-employed. Contribution: This survey provides evidence to improve COVID-19 vaccination uptake in South Africa.
first_indexed 2024-03-08T08:49:15Z
format Article
id doaj.art-5906b53e31634115a3559adcdabc8086
institution Directory Open Access Journal
issn 1025-9848
2071-9736
language Afrikaans
last_indexed 2024-03-08T08:49:15Z
publishDate 2024-02-01
publisher AOSIS
record_format Article
series Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
spelling doaj.art-5906b53e31634115a3559adcdabc80862024-02-01T12:37:47ZafrAOSISHealth SA Gesondheid: Journal of Interdisciplinary Health Sciences1025-98482071-97362024-02-01290e1e810.4102/hsag.v29i0.24681084COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adultsTanuja N. Gengiah0Donavan C. Naidoo1Nomcebo Maduma2Saien Govender3Sherishka Dhindayal4Lara Lewis5Center for the AIDS Programme of Research in South Africa (CAPRISA), Durban, South Africa; and Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, DurbanDiscipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, DurbanDiscipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, DurbanCenter for the AIDS Programme of Research in South Africa (CAPRISA), DurbanCenter for the AIDS Programme of Research in South Africa (CAPRISA), DurbanCenter for the AIDS Programme of Research in South Africa (CAPRISA), DurbanBackground: Concerns and misconceptions surrounding coronavirus disease 2019 (COVID-19) vaccines may account for vaccine hesitancy and low uptake. Aim: To determine prevalence of COVID-19 vaccine hesitancy, vaccine-related misconceptions, and predictors of vaccine hesitancy among South Africans. Setting: Community setting in five districts in KwaZulu- Natal province. Methods: Between August 20, 2021, and September 27, 2021, we conducted a cross-sectional survey, interviewing 300 unvaccinated adults amid the national vaccination campaign. Predictors of hesitancy were identified through multivariable logistic regression analysis. Results: Participants had a median age of 29 years (IQR: 23–39), 86.7% were Black African, 63.2% were male, 53.3% resided in rural communities, and 59.3% (95% CI: 53.8% – 64.9%) were classified as vaccine hesitant. The primary reason for not vaccinating was a lack of trust in the vaccine (62.1%). Factors associated with reduced vaccine hesitancy included age (participants aged 35–49 years: OR: 0.28, 95% CI: 0.18–0.64, p = 0.003; participants over 50 years: OR: 0.18, 95% CI: 0.07–0.47, p = 0.0004), previous COVID-19 infection (OR: 0.31, 95% CI: 0.11–0.87, p = 0.03), and receiving vaccine information from healthcare workers (OR: 0.32, 95% CI: 0.10–1.0, p = 0.05). Unemployed (OR: 2.14, 95% CI: 1.1–4.2, p = 0.03) and self-employed individuals (OR: 2.98, 95% CI: 1.27–7.02, p = 0.01) were more likely to be vaccine hesitant. Conclusion: COVID-19 vaccine hesitancy rates are high in KwaZulu-Natal. Uptake could be enhanced by healthcare workers leading information campaigns with messages targeting younger individuals, the unemployed, and the self-employed. Contribution: This survey provides evidence to improve COVID-19 vaccination uptake in South Africa.https://hsag.co.za/index.php/hsag/article/view/2468covid-19vaccinehesitancyvaccinationsurveysouth africa.
spellingShingle Tanuja N. Gengiah
Donavan C. Naidoo
Nomcebo Maduma
Saien Govender
Sherishka Dhindayal
Lara Lewis
COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults
Health SA Gesondheid: Journal of Interdisciplinary Health Sciences
covid-19
vaccine
hesitancy
vaccination
survey
south africa.
title COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults
title_full COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults
title_fullStr COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults
title_full_unstemmed COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults
title_short COVID-19 vaccine hesitancy in KwaZulu-Natal, South Africa: A survey of unvaccinated adults
title_sort covid 19 vaccine hesitancy in kwazulu natal south africa a survey of unvaccinated adults
topic covid-19
vaccine
hesitancy
vaccination
survey
south africa.
url https://hsag.co.za/index.php/hsag/article/view/2468
work_keys_str_mv AT tanujangengiah covid19vaccinehesitancyinkwazulunatalsouthafricaasurveyofunvaccinatedadults
AT donavancnaidoo covid19vaccinehesitancyinkwazulunatalsouthafricaasurveyofunvaccinatedadults
AT nomcebomaduma covid19vaccinehesitancyinkwazulunatalsouthafricaasurveyofunvaccinatedadults
AT saiengovender covid19vaccinehesitancyinkwazulunatalsouthafricaasurveyofunvaccinatedadults
AT sherishkadhindayal covid19vaccinehesitancyinkwazulunatalsouthafricaasurveyofunvaccinatedadults
AT laralewis covid19vaccinehesitancyinkwazulunatalsouthafricaasurveyofunvaccinatedadults