The injections of mitochondrial fusion promoter M1 during proestrus disrupt the progesterone secretion and the estrous cycle in the mouse

Abstract After ovulation, the mitochondrial enzyme CYP11A1 cleavage the cholesterol into pregnenolone for progesterone synthesis, suggesting that mitochondrial dynamics play a vital role in the female reproductive system. The changes in the mitochondria dynamics throughout the ovarian cycle have bee...

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Bibliographic Details
Main Authors: Yovita Permata Budi, Meng-Chieh Hsu, Yi-Chun Lin, Yue-Jia Lee, Hsin-Yi Chiu, Chih-Hsien Chiu, Yi-Fan Jiang
Format: Article
Language:English
Published: Nature Portfolio 2023-02-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-29608-7