Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration

Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active β-catenin protein was present during limb regenerati...

Full description

Bibliographic Details
Main Authors: Sabina Wischin, Cristina Castañeda-Patlán, Martha Robles-Flores, Jesús Chimal-Monroy
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Data in Brief
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2352340917300677
_version_ 1818558275114762240
author Sabina Wischin
Cristina Castañeda-Patlán
Martha Robles-Flores
Jesús Chimal-Monroy
author_facet Sabina Wischin
Cristina Castañeda-Patlán
Martha Robles-Flores
Jesús Chimal-Monroy
author_sort Sabina Wischin
collection DOAJ
description Limb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active β-catenin protein was present during limb regeneration in some Leydig cells in the epithelium; after the chemical treatment, it was observed in more Leydig cells. In addition, the chemical agonist of Wnt generated distinct limb malformation.
first_indexed 2024-12-14T00:10:29Z
format Article
id doaj.art-590b7dcca56e4e92ab9c3e3b68ea013b
institution Directory Open Access Journal
issn 2352-3409
language English
last_indexed 2024-12-14T00:10:29Z
publishDate 2017-04-01
publisher Elsevier
record_format Article
series Data in Brief
spelling doaj.art-590b7dcca56e4e92ab9c3e3b68ea013b2022-12-21T23:25:46ZengElsevierData in Brief2352-34092017-04-0111C56256610.1016/j.dib.2017.02.048Data on chemical activation of Wnt/β-catenin during axolotl limb regenerationSabina Wischin0Cristina Castañeda-Patlán1Martha Robles-Flores2Jesús Chimal-Monroy3Departamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico DF 04510, MexicoDepartamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria,, Mexico DF 04510, MexicoDepartamento de Bioquímica, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad Universitaria,, Mexico DF 04510, MexicoDepartamento de Medicina Genómica y Toxicología Ambiental, Instituto de Investigaciones Biomédicas, Universidad Nacional Autónoma de México, Mexico DF 04510, MexicoLimb amputation in axolotls was performed to obtain data demonstrating that a chemical agonist of Wnt (int-related protein)/β-catenin signalling can have a role in axolotl limb regeneration (Wischin et al., 2017) [1]. The data revealed that active β-catenin protein was present during limb regeneration in some Leydig cells in the epithelium; after the chemical treatment, it was observed in more Leydig cells. In addition, the chemical agonist of Wnt generated distinct limb malformation.http://www.sciencedirect.com/science/article/pii/S2352340917300677Limb regenerationWnt signaling
spellingShingle Sabina Wischin
Cristina Castañeda-Patlán
Martha Robles-Flores
Jesús Chimal-Monroy
Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
Data in Brief
Limb regeneration
Wnt signaling
title Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
title_full Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
title_fullStr Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
title_full_unstemmed Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
title_short Data on chemical activation of Wnt/β-catenin during axolotl limb regeneration
title_sort data on chemical activation of wnt β catenin during axolotl limb regeneration
topic Limb regeneration
Wnt signaling
url http://www.sciencedirect.com/science/article/pii/S2352340917300677
work_keys_str_mv AT sabinawischin dataonchemicalactivationofwntbcateninduringaxolotllimbregeneration
AT cristinacastanedapatlan dataonchemicalactivationofwntbcateninduringaxolotllimbregeneration
AT martharoblesflores dataonchemicalactivationofwntbcateninduringaxolotllimbregeneration
AT jesuschimalmonroy dataonchemicalactivationofwntbcateninduringaxolotllimbregeneration