Ocular tuberculosis masquerading as atypical ocular toxoplasmosis

Ocular tuberculosis is a great mimicker of various uveitis entities. We present a case of a 29-year-old male who came in with blurring of vision and floaters in the left eye. On examination, the left eye had anterior chamber cells and vitritis associated with retinitis. He had no other symptoms. The...

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Main Authors: Bromeo, Albert John, Lerit, Sweet Jorlene, Arcinue, Cheryl
Format: Article
Language:English
Published: German Medical Science GMS Publishing House 2023-09-01
Series:GMS Ophthalmology Cases
Subjects:
Online Access:http://www.egms.de/static/en/journals/oc/2023-13/oc000227.shtml
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author Bromeo, Albert John
Lerit, Sweet Jorlene
Arcinue, Cheryl
author_facet Bromeo, Albert John
Lerit, Sweet Jorlene
Arcinue, Cheryl
author_sort Bromeo, Albert John
collection DOAJ
description Ocular tuberculosis is a great mimicker of various uveitis entities. We present a case of a 29-year-old male who came in with blurring of vision and floaters in the left eye. On examination, the left eye had anterior chamber cells and vitritis associated with retinitis. He had no other symptoms. The initial presentation was consistent with ocular toxoplasmosis, and he was started on oral sulfamethoxazole-trimethoprim and showed a good response to the treatment. However, work-up revealed negative toxoplasma antibody titers but a positive inefeon-gamma release assay test and Mantoux test, making the diagnosis of ocular tuberculosis more likely. The patient was shifted to antituberculous therapy, which eventually resulted in the resolution of the inflammation with a recovery of the visual acuity. The diagnosis of ocular tuberculosis requires a detailed medical history as well as microbiologic and immunologic studies. A high index of suspicion by the treating ophthalmologist is necessary to reveal the diagnosis.
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spelling doaj.art-590e1e457bab428785207fd3adef90d92023-11-13T11:51:36ZengGerman Medical Science GMS Publishing HouseGMS Ophthalmology Cases2193-14962023-09-0113Doc1910.3205/oc000227Ocular tuberculosis masquerading as atypical ocular toxoplasmosisBromeo, Albert John0Lerit, Sweet Jorlene1Arcinue, Cheryl2Asian Eye Institute, Makati, PhilippinesAsian Eye Institute, Makati, PhilippinesAsian Eye Institute, Makati, PhilippinesOcular tuberculosis is a great mimicker of various uveitis entities. We present a case of a 29-year-old male who came in with blurring of vision and floaters in the left eye. On examination, the left eye had anterior chamber cells and vitritis associated with retinitis. He had no other symptoms. The initial presentation was consistent with ocular toxoplasmosis, and he was started on oral sulfamethoxazole-trimethoprim and showed a good response to the treatment. However, work-up revealed negative toxoplasma antibody titers but a positive inefeon-gamma release assay test and Mantoux test, making the diagnosis of ocular tuberculosis more likely. The patient was shifted to antituberculous therapy, which eventually resulted in the resolution of the inflammation with a recovery of the visual acuity. The diagnosis of ocular tuberculosis requires a detailed medical history as well as microbiologic and immunologic studies. A high index of suspicion by the treating ophthalmologist is necessary to reveal the diagnosis.http://www.egms.de/static/en/journals/oc/2023-13/oc000227.shtmltuberculosistoxoplasmosisuveitisretinitismasquerade syndrome
spellingShingle Bromeo, Albert John
Lerit, Sweet Jorlene
Arcinue, Cheryl
Ocular tuberculosis masquerading as atypical ocular toxoplasmosis
GMS Ophthalmology Cases
tuberculosis
toxoplasmosis
uveitis
retinitis
masquerade syndrome
title Ocular tuberculosis masquerading as atypical ocular toxoplasmosis
title_full Ocular tuberculosis masquerading as atypical ocular toxoplasmosis
title_fullStr Ocular tuberculosis masquerading as atypical ocular toxoplasmosis
title_full_unstemmed Ocular tuberculosis masquerading as atypical ocular toxoplasmosis
title_short Ocular tuberculosis masquerading as atypical ocular toxoplasmosis
title_sort ocular tuberculosis masquerading as atypical ocular toxoplasmosis
topic tuberculosis
toxoplasmosis
uveitis
retinitis
masquerade syndrome
url http://www.egms.de/static/en/journals/oc/2023-13/oc000227.shtml
work_keys_str_mv AT bromeoalbertjohn oculartuberculosismasqueradingasatypicaloculartoxoplasmosis
AT leritsweetjorlene oculartuberculosismasqueradingasatypicaloculartoxoplasmosis
AT arcinuecheryl oculartuberculosismasqueradingasatypicaloculartoxoplasmosis