A characteristic back support structure in the bisphenol A-binding pocket in the human nuclear receptor ERRγ.

A characteristic back support structure in the bisphenol A-binding pocket in the human nuclear receptor ERRγ.

The endocrine disruptor bisphenol A (BPA) affects various genes and hormones even at merely physiological levels. We recently demonstrated that BPA binds strongly to human nuclear receptor estrogen-related receptor (ERR) γ and that the phenol-A group of BPA is in a receptacle pocket with essential a...

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Bibliographic Details
Main Authors: Xiaohui Liu, Ayami Matsushima, Miki Shimohigashi, Yasuyuki Shimohigashi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4076284?pdf=render

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