Chemical Modification of Chitosan for Efficient Vaccine Delivery

Chitosan, which exhibits good biocompatibility, safety, microbial degradation and other excellent performances, has found application in all walks of life. In the field of medicine, usage of chitosan for the delivery of vaccine is favored by a wide range of researchers. However, due to its own natur...

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Bibliographic Details
Main Authors: Lei Xing, Ya-Tong Fan, Tian-Jiao Zhou, Jia-Hui Gong, Lian-Hua Cui, Ki-Hyun Cho, Yun-Jaie Choi, Hu-Lin Jiang, Chong-Su Cho
Format: Article
Language:English
Published: MDPI AG 2018-01-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/23/2/229
Description
Summary:Chitosan, which exhibits good biocompatibility, safety, microbial degradation and other excellent performances, has found application in all walks of life. In the field of medicine, usage of chitosan for the delivery of vaccine is favored by a wide range of researchers. However, due to its own natural limitations, its application has been constrained to the beginning of study. In order to improve the applicability for vaccine delivery, researchers have carried out various chemical modifications of chitosan. This review summarizes a variety of modification methods and applications of chitosan and its derivatives in the field of vaccine delivery.
ISSN:1420-3049