Sand Granules Ekstrak Biji Alpukat (Persea Americana Seed Extract) sebagai Larvasida Alami Pemberantas Demam Berdarah Dengue
Dengue hemorrhagic fever (DHF) threatens people in the rainy season. DHF is one of the major public health problems in Indonesia. These problems encourage an effort to eradicate Ae. aegypti larvae by using natural larvicide. One of the plants that can be used as natural larvicides is avocado seeds...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Universitas Tadulako
2020-03-01
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| Series: | Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) |
| Subjects: | |
| Online Access: | https://bestjournal.untad.ac.id/index.php/Galenika/article/view/13607 |
| _version_ | 1818772029040492544 |
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| author | Fef Rukminingsih Anasthasia Pujiastuti |
| author_facet | Fef Rukminingsih Anasthasia Pujiastuti |
| author_sort | Fef Rukminingsih |
| collection | DOAJ |
| description | Dengue hemorrhagic fever (DHF) threatens people in the rainy season. DHF is one of the major public health problems in Indonesia. These problems encourage an effort to eradicate Ae. aegypti larvae by using natural larvicide. One of the plants that can be used as natural larvicides is avocado seeds (Persea americana Seed) which contain saponin. This study aims to determine the larvacidal activity of avocado seed extract sandgranules with LC50 of 8.87 mg.mL-1 against Ae. aegypti larvae. This study is an experimental research with a complete random design in a unidirectional pattern. The independent variable in this study is the variation concentration of Explotab as a disintegrant agent ie 2, 3, and 4%. Sand granules of avocado seed extract are made by wet granulation method. Results of the larvacidal activity test of avocado seed extract sand granules were analyzed by calculating the percentage of larvae mortality and statistical analysis using SPSS. The results of this study is the larvacidal activity of pure avocado seed extract with LC50 8.87 mg. L-1 is greater than the avocado seed extract sand granules. The addition of Explotab did not affect the total larvae mortality, but there was a significant difference in larvae mortality at 5 hours of sand granules exposure with explotab concentration of 3% and 4% (a significance value <0.05). |
| first_indexed | 2024-12-18T10:02:51Z |
| format | Article |
| id | doaj.art-5914af7ef4c24fd1909b0f6a61e0f5d9 |
| institution | Directory Open Access Journal |
| issn | 2442-7284 2442-8744 |
| language | English |
| last_indexed | 2024-12-18T10:02:51Z |
| publishDate | 2020-03-01 |
| publisher | Universitas Tadulako |
| record_format | Article |
| series | Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) |
| spelling | doaj.art-5914af7ef4c24fd1909b0f6a61e0f5d92022-12-21T21:11:37ZengUniversitas TadulakoJurnal Farmasi Galenika (Galenika Journal of Pharmacy)2442-72842442-87442020-03-0161849310.22487/j24428744.2020.v6.i1.1360713607Sand Granules Ekstrak Biji Alpukat (Persea Americana Seed Extract) sebagai Larvasida Alami Pemberantas Demam Berdarah DengueFef Rukminingsih0Anasthasia Pujiastuti1Politeknik Katolik MangunwijayaPoliteknik Katolik MangunwijayaDengue hemorrhagic fever (DHF) threatens people in the rainy season. DHF is one of the major public health problems in Indonesia. These problems encourage an effort to eradicate Ae. aegypti larvae by using natural larvicide. One of the plants that can be used as natural larvicides is avocado seeds (Persea americana Seed) which contain saponin. This study aims to determine the larvacidal activity of avocado seed extract sandgranules with LC50 of 8.87 mg.mL-1 against Ae. aegypti larvae. This study is an experimental research with a complete random design in a unidirectional pattern. The independent variable in this study is the variation concentration of Explotab as a disintegrant agent ie 2, 3, and 4%. Sand granules of avocado seed extract are made by wet granulation method. Results of the larvacidal activity test of avocado seed extract sand granules were analyzed by calculating the percentage of larvae mortality and statistical analysis using SPSS. The results of this study is the larvacidal activity of pure avocado seed extract with LC50 8.87 mg. L-1 is greater than the avocado seed extract sand granules. The addition of Explotab did not affect the total larvae mortality, but there was a significant difference in larvae mortality at 5 hours of sand granules exposure with explotab concentration of 3% and 4% (a significance value <0.05).https://bestjournal.untad.ac.id/index.php/Galenika/article/view/13607sand granulesavocado seed extractexplotablarvacidal activity |
| spellingShingle | Fef Rukminingsih Anasthasia Pujiastuti Sand Granules Ekstrak Biji Alpukat (Persea Americana Seed Extract) sebagai Larvasida Alami Pemberantas Demam Berdarah Dengue Jurnal Farmasi Galenika (Galenika Journal of Pharmacy) sand granules avocado seed extract explotab larvacidal activity |
| title | Sand Granules Ekstrak Biji Alpukat (Persea Americana Seed Extract) sebagai Larvasida Alami Pemberantas Demam Berdarah Dengue |
| title_full | Sand Granules Ekstrak Biji Alpukat (Persea Americana Seed Extract) sebagai Larvasida Alami Pemberantas Demam Berdarah Dengue |
| title_fullStr | Sand Granules Ekstrak Biji Alpukat (Persea Americana Seed Extract) sebagai Larvasida Alami Pemberantas Demam Berdarah Dengue |
| title_full_unstemmed | Sand Granules Ekstrak Biji Alpukat (Persea Americana Seed Extract) sebagai Larvasida Alami Pemberantas Demam Berdarah Dengue |
| title_short | Sand Granules Ekstrak Biji Alpukat (Persea Americana Seed Extract) sebagai Larvasida Alami Pemberantas Demam Berdarah Dengue |
| title_sort | sand granules ekstrak biji alpukat persea americana seed extract sebagai larvasida alami pemberantas demam berdarah dengue |
| topic | sand granules avocado seed extract explotab larvacidal activity |
| url | https://bestjournal.untad.ac.id/index.php/Galenika/article/view/13607 |
| work_keys_str_mv | AT fefrukminingsih sandgranulesekstrakbijialpukatperseaamericanaseedextractsebagailarvasidaalamipemberantasdemamberdarahdengue AT anasthasiapujiastuti sandgranulesekstrakbijialpukatperseaamericanaseedextractsebagailarvasidaalamipemberantasdemamberdarahdengue |