Landscape and perspectives of macrophage -targeted cancer therapy in clinical trials

Landscape and perspectives of macrophage -targeted cancer therapy in clinical trials

Tumor-associated macrophages (TAMs) exert integrated effects in all aspects of tumor progression, including tumor cell proliferation, angiogenesis, invasion, and metastasis. Recently, considerable preclinical and clinical trials have demonstrated that TAM-targeted therapy is an effective antitumor t...

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Bibliographic Details
Main Authors: Shuhang Wang, Yuqi Yang, Peiwen Ma, Huiyao Huang, Qiyu Tang, Huilei Miao, Yuan Fang, Ning Jiang, Yandong Li, Qi Zhu, Wei Tao, Yan Zha, Ning Li
Format: Article
Language:English
Published: Elsevier 2022-03-01
Series:Molecular Therapy: Oncolytics
Subjects:
tumor-associated macrophages
cancer
therapy
clinical trials
combination
CAR macrophages
Online Access:http://www.sciencedirect.com/science/article/pii/S2372770522000365

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