Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性)
合成3种双核铂类配合物[{Pt(H2O)2I}μ—OOC—(CH2—)nCOO—{Pt(H2O)2I}](1~3)(n=0,1,2).用元素分析、摩尔电导、差热热重分析、红外光谱、紫外光谱和核磁共振氢谱等方法对其进行了表征.体外抗肿瘤活性表明,配合物1和3对多种人的肿瘤细胞有较高的活性,配合物2没有抗肿瘤活性....
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | zho |
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Zhejiang University Press
2003-03-01
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| Series: | Zhejiang Daxue xuebao. Lixue ban |
| Subjects: | |
| Online Access: | https://doi.org/zjup/1008-9497.2003.30.2.192-195 |
| _version_ | 1797236473013993472 |
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| author | ZHANGJin-chao(张金超) LIWen-xian(李文献) GONGYu-qiu(龚钰秋) ZHENGXiao-ming(郑小明) CUIJing-rong(崔景荣) WUJun(吴军) WANGRui-qing(王瑞卿) |
| author_facet | ZHANGJin-chao(张金超) LIWen-xian(李文献) GONGYu-qiu(龚钰秋) ZHENGXiao-ming(郑小明) CUIJing-rong(崔景荣) WUJun(吴军) WANGRui-qing(王瑞卿) |
| author_sort | ZHANGJin-chao(张金超) |
| collection | DOAJ |
| description | 合成3种双核铂类配合物[{Pt(H2O)2I}μ—OOC—(CH2—)nCOO—{Pt(H2O)2I}](1~3)(n=0,1,2).用元素分析、摩尔电导、差热热重分析、红外光谱、紫外光谱和核磁共振氢谱等方法对其进行了表征.体外抗肿瘤活性表明,配合物1和3对多种人的肿瘤细胞有较高的活性,配合物2没有抗肿瘤活性. |
| first_indexed | 2024-04-24T17:04:24Z |
| format | Article |
| id | doaj.art-5919afe4a09e434898a5c34b4f5ad6c4 |
| institution | Directory Open Access Journal |
| issn | 1008-9497 |
| language | zho |
| last_indexed | 2024-04-24T17:04:24Z |
| publishDate | 2003-03-01 |
| publisher | Zhejiang University Press |
| record_format | Article |
| series | Zhejiang Daxue xuebao. Lixue ban |
| spelling | doaj.art-5919afe4a09e434898a5c34b4f5ad6c42024-03-29T01:58:19ZzhoZhejiang University PressZhejiang Daxue xuebao. Lixue ban1008-94972003-03-01302192195zjup/1008-9497.2003.30.2.192-195Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性)ZHANGJin-chao(张金超)0LIWen-xian(李文献)1GONGYu-qiu(龚钰秋)2ZHENGXiao-ming(郑小明)3CUIJing-rong(崔景荣)4WUJun(吴军)5WANGRui-qing(王瑞卿)6 1.Department of Chemistry, Zhejiang University, Hangzhou 310028, China( 1.浙江大学化学系，浙江 杭州 310028) 1.Department of Chemistry, Zhejiang University, Hangzhou 310028, China( 1.浙江大学化学系，浙江 杭州 310028) 1.Department of Chemistry, Zhejiang University, Hangzhou 310028, China( 1.浙江大学化学系，浙江 杭州 310028) 1.Department of Chemistry, Zhejiang University, Hangzhou 310028, China( 1.浙江大学化学系，浙江 杭州 310028) 2.Laboratory of Natural and Biomimetic Drugs, Beijing University, Beijing 100083, China( 2.北京大学医学部天然药物与仿生药物国家重点实验室，北京 100083) 2.Laboratory of Natural and Biomimetic Drugs, Beijing University, Beijing 100083, China( 2.北京大学医学部天然药物与仿生药物国家重点实验室，北京 100083) 2.Laboratory of Natural and Biomimetic Drugs, Beijing University, Beijing 100083, China( 2.北京大学医学部天然药物与仿生药物国家重点实验室，北京 100083)合成3种双核铂类配合物[{Pt(H2O)2I}μ—OOC—(CH2—)nCOO—{Pt(H2O)2I}](1~3)(n=0,1,2).用元素分析、摩尔电导、差热热重分析、红外光谱、紫外光谱和核磁共振氢谱等方法对其进行了表征.体外抗肿瘤活性表明,配合物1和3对多种人的肿瘤细胞有较高的活性,配合物2没有抗肿瘤活性.https://doi.org/zjup/1008-9497.2003.30.2.192-195双核铂类配合物合成抗肿瘤活性 |
| spellingShingle | ZHANGJin-chao(张金超) LIWen-xian(李文献) GONGYu-qiu(龚钰秋) ZHENGXiao-ming(郑小明) CUIJing-rong(崔景荣) WUJun(吴军) WANGRui-qing(王瑞卿) Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性) Zhejiang Daxue xuebao. Lixue ban 双核铂类配合物 合成 抗肿瘤活性 |
| title | Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性) |
| title_full | Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性) |
| title_fullStr | Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性) |
| title_full_unstemmed | Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性) |
| title_short | Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性) |
| title_sort | synthesis and antitumor activities of new generation binuclear platinum complexes 新型双核铂类配合物的合成及其抗肿瘤活性 |
| topic | 双核铂类配合物 合成 抗肿瘤活性 |
| url | https://doi.org/zjup/1008-9497.2003.30.2.192-195 |
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