Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性)

Synthesis and antitumor activities of new generation binuclear platinum complexes(新型双核铂类配合物的合成及其抗肿瘤活性)

合成3种双核铂类配合物[{Pt(H2O)2I}μ—OOC—(CH2—)nCOO—{Pt(H2O)2I}](1~3)(n=0,1,2).用元素分析、摩尔电导、差热热重分析、红外光谱、紫外光谱和核磁共振氢谱等方法对其进行了表征.体外抗肿瘤活性表明,配合物1和3对多种人的肿瘤细胞有较高的活性,配合物2没有抗肿瘤活性....

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Bibliographic Details
Main Authors: ZHANGJin-chao(张金超), LIWen-xian(李文献), GONGYu-qiu(龚钰秋), ZHENGXiao-ming(郑小明), CUIJing-rong(崔景荣), WUJun(吴军), WANGRui-qing(王瑞卿)
Format: Article
Language:zho
Published: Zhejiang University Press 2003-03-01
Series:Zhejiang Daxue xuebao. Lixue ban
Subjects:
双核铂类配合物
合成
抗肿瘤活性
Online Access:https://doi.org/zjup/1008-9497.2003.30.2.192-195

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