Swine T-Cells and Specific Antibodies Evoked by Peptide Dendrimers Displaying Different FMDV T-Cell Epitopes

Swine T-Cells and Specific Antibodies Evoked by Peptide Dendrimers Displaying Different FMDV T-Cell Epitopes

Dendrimeric peptide constructs based on a lysine core that comprises both B- and T-cell epitopes of foot-and-mouth disease virus (FMDV) have proven a successful strategy for the development of FMD vaccines. Specifically, B2T dendrimers displaying two copies of the major type O FMDV antigenic B-cell...

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Bibliographic Details
Main Authors: Patricia de León, Rodrigo Cañas-Arranz, Sira Defaus, Elisa Torres, Mar Forner, María J. Bustos, Concepción Revilla, Javier Dominguez, David Andreu, Esther Blanco, Francisco Sobrino
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Immunology
Subjects:
foot-and-mouth disease virus
vaccines
dendrimer peptide
T cell phenotype
cytokine
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.621537/full

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