Current approach for the prosthesis patient mismatch

All prosthetic valves are at least mildly stenotic and have relatively high transvalvular pressure gradients that can be observed despite normal prosthesis function. Such gradients may be due to a mismatch between prosthesis effective orifice area (EOA) and patient's body size. Valve prosthesis...

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Main Authors: Asuman Biçer Yeşilay, Zekeriya Kaya, Recep Demirbağ
Format: Article
Language:English
Published: KARE Publishing 2013-06-01
Series:Türk Kardiyoloji Derneği Arşivi
Subjects:
Online Access:https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-35219
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author Asuman Biçer Yeşilay
Zekeriya Kaya
Recep Demirbağ
author_facet Asuman Biçer Yeşilay
Zekeriya Kaya
Recep Demirbağ
author_sort Asuman Biçer Yeşilay
collection DOAJ
description All prosthetic valves are at least mildly stenotic and have relatively high transvalvular pressure gradients that can be observed despite normal prosthesis function. Such gradients may be due to a mismatch between prosthesis effective orifice area (EOA) and patient's body size. Valve prosthesispatient mismatch (VP-PM) may occur due to mismatches of both parameters, the expected hemodynamic performance of the prosthesis and the cardiac output requirements of the patient, which are largely related to the body size at rest. In other words, a prosthesis may be adequate for patients with a small body surface area (BSA) but might become obstructive for patients with a large BSA. The only parameter that has proven to be consistently and realistically useful to predict and describe VP-PM is the effective orifice area index (EOAI). The projected EOAI was identified as the best parameter to predict the VP-PM occurrence after surgery. VP-PM has been known to be independently and significantly associated with clinical outcomes. Severe VP-PM has a significant impact on early and late mortality, whereas moderate VP-PM may have a significant effect on mortality only in vulnerable subsets of patients, and particularly in those with depressed LV systolic function. The surgeon's anticipation of VP-PM prior to surgery, and successfully implented preventive strategies can reduce the incidence of VP-PM. Preventive strategies to avoid VPPM should be individualized according to the anticipated severity of VP-PM and of the patient's baseline risk profile.
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spelling doaj.art-591d16122ca247e2a87fe38e4ae9fdaf2023-02-15T16:14:43ZengKARE PublishingTürk Kardiyoloji Derneği Arşivi1016-51692013-06-0141435436310.5543/tkda.2013.35219TKDA-35219Current approach for the prosthesis patient mismatchAsuman Biçer Yeşilay0Zekeriya Kaya1Recep Demirbağ2Department Of Cardiology, Harran University Faculty Of Medicine, Sanliurfa, TurkeyDepartment Of Cardiology, Harran University Faculty Of Medicine, Sanliurfa, TurkeyDepartment Of Cardiology, Harran University Faculty Of Medicine, Sanliurfa, TurkeyAll prosthetic valves are at least mildly stenotic and have relatively high transvalvular pressure gradients that can be observed despite normal prosthesis function. Such gradients may be due to a mismatch between prosthesis effective orifice area (EOA) and patient's body size. Valve prosthesispatient mismatch (VP-PM) may occur due to mismatches of both parameters, the expected hemodynamic performance of the prosthesis and the cardiac output requirements of the patient, which are largely related to the body size at rest. In other words, a prosthesis may be adequate for patients with a small body surface area (BSA) but might become obstructive for patients with a large BSA. The only parameter that has proven to be consistently and realistically useful to predict and describe VP-PM is the effective orifice area index (EOAI). The projected EOAI was identified as the best parameter to predict the VP-PM occurrence after surgery. VP-PM has been known to be independently and significantly associated with clinical outcomes. Severe VP-PM has a significant impact on early and late mortality, whereas moderate VP-PM may have a significant effect on mortality only in vulnerable subsets of patients, and particularly in those with depressed LV systolic function. The surgeon's anticipation of VP-PM prior to surgery, and successfully implented preventive strategies can reduce the incidence of VP-PM. Preventive strategies to avoid VPPM should be individualized according to the anticipated severity of VP-PM and of the patient's baseline risk profile.https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-35219equipment failureechocardiography; cardiovascular surgical procedures; heart valve prosthesis; practice guidelines as topic.
spellingShingle Asuman Biçer Yeşilay
Zekeriya Kaya
Recep Demirbağ
Current approach for the prosthesis patient mismatch
Türk Kardiyoloji Derneği Arşivi
equipment failure
echocardiography; cardiovascular surgical procedures; heart valve prosthesis; practice guidelines as topic.
title Current approach for the prosthesis patient mismatch
title_full Current approach for the prosthesis patient mismatch
title_fullStr Current approach for the prosthesis patient mismatch
title_full_unstemmed Current approach for the prosthesis patient mismatch
title_short Current approach for the prosthesis patient mismatch
title_sort current approach for the prosthesis patient mismatch
topic equipment failure
echocardiography; cardiovascular surgical procedures; heart valve prosthesis; practice guidelines as topic.
url https://jag.journalagent.com/z4/download_fulltext.asp?pdir=tkd&un=TKDA-35219
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AT zekeriyakaya currentapproachfortheprosthesispatientmismatch
AT recepdemirbag currentapproachfortheprosthesispatientmismatch