A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges

Nutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that are biologically active and possess capability for maintaining optimal health and benefits. These products play a significant role in human health care and its endurance, most importantly for the future thera...

Full description

Bibliographic Details
Main Authors: Vivek Puri, Manju Nagpal, Inderbir Singh, Manjinder Singh, Gitika Arora Dhingra, Kampanart Huanbutta, Divya Dheer, Ameya Sharma, Tanikan Sangnim
Format: Article
Language:English
Published: MDPI AG 2022-11-01
Series:Nutrients
Subjects:
Online Access:https://www.mdpi.com/2072-6643/14/21/4637
_version_ 1797466887408320512
author Vivek Puri
Manju Nagpal
Inderbir Singh
Manjinder Singh
Gitika Arora Dhingra
Kampanart Huanbutta
Divya Dheer
Ameya Sharma
Tanikan Sangnim
author_facet Vivek Puri
Manju Nagpal
Inderbir Singh
Manjinder Singh
Gitika Arora Dhingra
Kampanart Huanbutta
Divya Dheer
Ameya Sharma
Tanikan Sangnim
author_sort Vivek Puri
collection DOAJ
description Nutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that are biologically active and possess capability for maintaining optimal health and benefits. These products play a significant role in human health care and its endurance, most importantly for the future therapeutic development. Nutraceuticals have received recognition due to their nutritional benefits along with therapeutic effects and safety profile. Nutraceuticals are globally growing in the field of services such as health care promotion, disease reduction, etc. Various drug nutraceutical interactions have also been elaborated with various examples in this review. Several patents on nutraceuticals in agricultural applications and in various diseases have been stated in the last section of review, which confirms the exponential growth of nutraceuticals’ market value. Nutraceuticals have been used not only for nutrition but also as a support therapy for the prevention and treatment of various diseases, such as to reduce side effects of cancer chemotherapy and radiotherapy. Diverse novel nanoformulation approaches tend to overcome challenges involved in formulation development of nutraceuticals. Prior information on various interactions with drugs may help in preventing any deleterious effects of nutraceuticals products. Nanotechnology also leads to the generation of micronized dietary products and other nutraceutical supplements with improved health benefits. In this review article, the latest key findings (clinical studies) on nutraceuticals that show the therapeutic action of nutraceutical’s bioactive molecules on various diseases have also been discussed.
first_indexed 2024-03-09T18:45:57Z
format Article
id doaj.art-591e028b16e147ebbc0e1abd288e5cb8
institution Directory Open Access Journal
issn 2072-6643
language English
last_indexed 2024-03-09T18:45:57Z
publishDate 2022-11-01
publisher MDPI AG
record_format Article
series Nutrients
spelling doaj.art-591e028b16e147ebbc0e1abd288e5cb82023-11-24T06:14:47ZengMDPI AGNutrients2072-66432022-11-011421463710.3390/nu14214637A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation ChallengesVivek Puri0Manju Nagpal1Inderbir Singh2Manjinder Singh3Gitika Arora Dhingra4Kampanart Huanbutta5Divya Dheer6Ameya Sharma7Tanikan Sangnim8School of Pharmacy, Chitkara University, Baddi 174103, Himachal Pradesh, IndiaCollege of Pharmacy, Chitkara University, Rajpura 140401, Punjab, IndiaCollege of Pharmacy, Chitkara University, Rajpura 140401, Punjab, IndiaCollege of Pharmacy, Chitkara University, Rajpura 140401, Punjab, IndiaNCRD’s Sterling Institute of Pharmacy, Nerul, Navi Mumbai 400706, Maharashtra, IndiaSchool of Pharmacy, Eastern Asia University, Pathum Thani 12110, Tanyaburi, ThailandSchool of Pharmacy, Chitkara University, Baddi 174103, Himachal Pradesh, IndiaSchool of Pharmacy, Chitkara University, Baddi 174103, Himachal Pradesh, IndiaFaculty of Pharmaceutical Sciences, Burapha University, Chonburi 20131, Muang, ThailandNutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that are biologically active and possess capability for maintaining optimal health and benefits. These products play a significant role in human health care and its endurance, most importantly for the future therapeutic development. Nutraceuticals have received recognition due to their nutritional benefits along with therapeutic effects and safety profile. Nutraceuticals are globally growing in the field of services such as health care promotion, disease reduction, etc. Various drug nutraceutical interactions have also been elaborated with various examples in this review. Several patents on nutraceuticals in agricultural applications and in various diseases have been stated in the last section of review, which confirms the exponential growth of nutraceuticals’ market value. Nutraceuticals have been used not only for nutrition but also as a support therapy for the prevention and treatment of various diseases, such as to reduce side effects of cancer chemotherapy and radiotherapy. Diverse novel nanoformulation approaches tend to overcome challenges involved in formulation development of nutraceuticals. Prior information on various interactions with drugs may help in preventing any deleterious effects of nutraceuticals products. Nanotechnology also leads to the generation of micronized dietary products and other nutraceutical supplements with improved health benefits. In this review article, the latest key findings (clinical studies) on nutraceuticals that show the therapeutic action of nutraceutical’s bioactive molecules on various diseases have also been discussed.https://www.mdpi.com/2072-6643/14/21/4637cardiovascular diseasesinteractionsnutritionpreventiontherapeutics
spellingShingle Vivek Puri
Manju Nagpal
Inderbir Singh
Manjinder Singh
Gitika Arora Dhingra
Kampanart Huanbutta
Divya Dheer
Ameya Sharma
Tanikan Sangnim
A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
Nutrients
cardiovascular diseases
interactions
nutrition
prevention
therapeutics
title A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
title_full A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
title_fullStr A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
title_full_unstemmed A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
title_short A Comprehensive Review on Nutraceuticals: Therapy Support and Formulation Challenges
title_sort comprehensive review on nutraceuticals therapy support and formulation challenges
topic cardiovascular diseases
interactions
nutrition
prevention
therapeutics
url https://www.mdpi.com/2072-6643/14/21/4637
work_keys_str_mv AT vivekpuri acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT manjunagpal acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT inderbirsingh acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT manjindersingh acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT gitikaaroradhingra acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT kampanarthuanbutta acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT divyadheer acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT ameyasharma acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT tanikansangnim acomprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT vivekpuri comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT manjunagpal comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT inderbirsingh comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT manjindersingh comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT gitikaaroradhingra comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT kampanarthuanbutta comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT divyadheer comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT ameyasharma comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges
AT tanikansangnim comprehensivereviewonnutraceuticalstherapysupportandformulationchallenges