Tailor-Made Detection of Individual Phosphorylated and Non-Phosphorylated EPIYA-Motifs of <i>Helicobacter pylori</i> Oncoprotein CagA

Tailor-Made Detection of Individual Phosphorylated and Non-Phosphorylated EPIYA-Motifs of <i>Helicobacter pylori</i> Oncoprotein CagA

The gastric pathogen and carcinogen <i>Helicobacter pylori</i> <i>(H. pylori)</i> encodes a type IV secretion system for translocation of the effector protein CagA into host cells. Injected CagA becomes tyrosine-phosphorylated at the five amino acid residue Glutamate-Proline-...

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Bibliographic Details
Main Authors:	Suneesh Kumar Pachathundikandi, Andrés Julián Gutiérrez-Escobar, Nicole Tegtmeyer
Format:	Article
Language:	English
Published:	MDPI AG 2019-08-01
Series:	Cancers
Subjects:	CagA <i>cag</i>PAI dotblot EPIYA motifs <i>Helicobacter pylori</i> signaling type IV secretion Abl and Src tyrosine kinases
Online Access:	https://www.mdpi.com/2072-6694/11/8/1163

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