Radioprotective Effects from Propolis: A Review
Propolis is a natural bee-produced substance with antimicrobial, anti-inflammatory, and wound-healing properties, containing some components from the leaves, buds and resins of plants. It has been used for centuries for various health benefits. In this manuscript, our group reviewed the radioprotect...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-08-01
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| Series: | Molecules |
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| Online Access: | https://www.mdpi.com/1420-3049/28/15/5842 |
| _version_ | 1797586227171426304 |
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| author | Blanca Ibáñez Ana Melero Alegría Montoro Nadia San Onofre Jose M. Soriano |
| author_facet | Blanca Ibáñez Ana Melero Alegría Montoro Nadia San Onofre Jose M. Soriano |
| author_sort | Blanca Ibáñez |
| collection | DOAJ |
| description | Propolis is a natural bee-produced substance with antimicrobial, anti-inflammatory, and wound-healing properties, containing some components from the leaves, buds and resins of plants. It has been used for centuries for various health benefits. In this manuscript, our group reviewed the radioprotective effect of propolis using PubMed and Embase, and our review was conducted according to the PRISMA statement. Finally, 27 articles were included in this review, which includes the radioprotective effect of propolis from cell-based studies (<i>n</i> = 8), animal models (<i>n</i> = 14), and human trials (<i>n</i> = 5). Results reflected that the dosage forms of propolis extracted in the scientific literature were ethanolic extracts of propolis, a water-soluble derivate of propolis, or capsules. The efficacy of the radioprotective properties from propolis is extracted from the bibliography, as several compounds of this resinous mixture individually or synergistically are possible candidates that have the radioprotective effect. In fact, studies prior to 2011 lacked a comprehensive characterization of propolis due to the variability in active compounds among different batches of propolis and were limited to analytical techniques. Furthermore, in this manuscript, we have selected studies to include primarily propolis types from Brazil, Croatia, Egypt, European countries, and those commercialized in Spain. They all contained ethanolic extract of propolis (EEP) and were influenced by different dosage forms. EEP showed a significant presence of lipophilic bioactive compounds like flavones, flavonols, and flavanones. |
| first_indexed | 2024-03-11T00:20:27Z |
| format | Article |
| id | doaj.art-59230dafdd034f91a768dc63ab8e0fd7 |
| institution | Directory Open Access Journal |
| issn | 1420-3049 |
| language | English |
| last_indexed | 2024-03-11T00:20:27Z |
| publishDate | 2023-08-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Molecules |
| spelling | doaj.art-59230dafdd034f91a768dc63ab8e0fd72023-11-18T23:19:35ZengMDPI AGMolecules1420-30492023-08-012815584210.3390/molecules28155842Radioprotective Effects from Propolis: A ReviewBlanca Ibáñez0Ana Melero1Alegría Montoro2Nadia San Onofre3Jose M. Soriano4Food & Health Laboratory, Institute of Materials Science, University of Valencia, 46980 Paterna, SpainDepartment of Pharmacy and Pharmaceutical Technology and Parasitology, Faculty of Pharmacy, University of Valencia, 46100 Burjassot, SpainService of Radiological Protection, Clinical Area of Medical Image, University and Polytechnic La Fe Hospital, 46026 Valencia, SpainFood & Health Laboratory, Institute of Materials Science, University of Valencia, 46980 Paterna, SpainFood & Health Laboratory, Institute of Materials Science, University of Valencia, 46980 Paterna, SpainPropolis is a natural bee-produced substance with antimicrobial, anti-inflammatory, and wound-healing properties, containing some components from the leaves, buds and resins of plants. It has been used for centuries for various health benefits. In this manuscript, our group reviewed the radioprotective effect of propolis using PubMed and Embase, and our review was conducted according to the PRISMA statement. Finally, 27 articles were included in this review, which includes the radioprotective effect of propolis from cell-based studies (<i>n</i> = 8), animal models (<i>n</i> = 14), and human trials (<i>n</i> = 5). Results reflected that the dosage forms of propolis extracted in the scientific literature were ethanolic extracts of propolis, a water-soluble derivate of propolis, or capsules. The efficacy of the radioprotective properties from propolis is extracted from the bibliography, as several compounds of this resinous mixture individually or synergistically are possible candidates that have the radioprotective effect. In fact, studies prior to 2011 lacked a comprehensive characterization of propolis due to the variability in active compounds among different batches of propolis and were limited to analytical techniques. Furthermore, in this manuscript, we have selected studies to include primarily propolis types from Brazil, Croatia, Egypt, European countries, and those commercialized in Spain. They all contained ethanolic extract of propolis (EEP) and were influenced by different dosage forms. EEP showed a significant presence of lipophilic bioactive compounds like flavones, flavonols, and flavanones.https://www.mdpi.com/1420-3049/28/15/5842radioprotectionpropolisradiation |
| spellingShingle | Blanca Ibáñez Ana Melero Alegría Montoro Nadia San Onofre Jose M. Soriano Radioprotective Effects from Propolis: A Review Molecules radioprotection propolis radiation |
| title | Radioprotective Effects from Propolis: A Review |
| title_full | Radioprotective Effects from Propolis: A Review |
| title_fullStr | Radioprotective Effects from Propolis: A Review |
| title_full_unstemmed | Radioprotective Effects from Propolis: A Review |
| title_short | Radioprotective Effects from Propolis: A Review |
| title_sort | radioprotective effects from propolis a review |
| topic | radioprotection propolis radiation |
| url | https://www.mdpi.com/1420-3049/28/15/5842 |
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