To compare the effect of warm ischemia time and its significance, if any - open versus laparoscopic donor nephrectomy
Introduction: The traditional open live-donor nephrectomy (OLDN) was intended to be replaced when the laparoscopic live-donor nephrectomy (LLDN) was introduced in 1995. The aim of the study is to analyze the effect of warm ischemia time (WIT) in open versus laparoscopic donor nephrectomy. Materials...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Indian Journal of Transplantation |
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| Online Access: | http://www.ijtonline.in/article.asp?issn=2212-0017;year=2023;volume=17;issue=4;spage=431;epage=435;aulast=Punia |
| _version_ | 1827309206511812608 |
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| author | Sahil Punia Nripesh Sadasukhi Trilok Chand Sadasukhi Hotilal L Gupta Manish Gupta Ashish Sharma |
| author_facet | Sahil Punia Nripesh Sadasukhi Trilok Chand Sadasukhi Hotilal L Gupta Manish Gupta Ashish Sharma |
| author_sort | Sahil Punia |
| collection | DOAJ |
| description | Introduction: The traditional open live-donor nephrectomy (OLDN) was intended to be replaced when the laparoscopic live-donor nephrectomy (LLDN) was introduced in 1995. The aim of the study is to analyze the effect of warm ischemia time (WIT) in open versus laparoscopic donor nephrectomy. Materials and Methods: The study included 200 consecutive donor transplants. Kidneys were retrieved by open donor nephrectomy vs. laparoscopic donor nephrectomy. We prospectively recorded the operative data, warm–cold ischemia time, graft function, hospital stay, return to work, and donor recovery. Results: A total of 200 participants were enrolled in the study dividing 100 per group in open and laparoscopic renal transplantation. The demographic data were comparable in both groups. The average WIT was 4.63 ± 1.4 min for the open group and 4.98 ± 1.82 min for the laparoscopic group (P < 0.05). In both groups, the average cold ischemia time was comparable. Both groups' postoperative urinary output, serum creatinine, and graft function exhibited no significant changes. Conclusion: The study demonstrates that varied degrees of WIT within the scope of this study have no negative impact on the outcomes of allografts obtained laparoscopically or openly. As a result, rushing renal artery ligation and division and kidney extraction to reduce WIT at the price of hurting the kidney transplant and donor are not realistic. However, it is uncertain how long the WIT safety window will stay open. This discovery may enable more urologists to undertake LLDN without the previously considered detrimental impact of WIT in compared to OLDN. |
| first_indexed | 2024-04-24T19:27:34Z |
| format | Article |
| id | doaj.art-5926cdb2a44d4ca4a1b65dfd3a8cfc94 |
| institution | Directory Open Access Journal |
| issn | 2212-0017 2212-0025 |
| language | English |
| last_indexed | 2024-04-24T19:27:34Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Indian Journal of Transplantation |
| spelling | doaj.art-5926cdb2a44d4ca4a1b65dfd3a8cfc942024-03-25T14:41:57ZengWolters Kluwer Medknow PublicationsIndian Journal of Transplantation2212-00172212-00252023-01-0117443143510.4103/ijot.ijot_33_23To compare the effect of warm ischemia time and its significance, if any - open versus laparoscopic donor nephrectomySahil PuniaNripesh SadasukhiTrilok Chand SadasukhiHotilal L GuptaManish GuptaAshish SharmaIntroduction: The traditional open live-donor nephrectomy (OLDN) was intended to be replaced when the laparoscopic live-donor nephrectomy (LLDN) was introduced in 1995. The aim of the study is to analyze the effect of warm ischemia time (WIT) in open versus laparoscopic donor nephrectomy. Materials and Methods: The study included 200 consecutive donor transplants. Kidneys were retrieved by open donor nephrectomy vs. laparoscopic donor nephrectomy. We prospectively recorded the operative data, warm–cold ischemia time, graft function, hospital stay, return to work, and donor recovery. Results: A total of 200 participants were enrolled in the study dividing 100 per group in open and laparoscopic renal transplantation. The demographic data were comparable in both groups. The average WIT was 4.63 ± 1.4 min for the open group and 4.98 ± 1.82 min for the laparoscopic group (P < 0.05). In both groups, the average cold ischemia time was comparable. Both groups' postoperative urinary output, serum creatinine, and graft function exhibited no significant changes. Conclusion: The study demonstrates that varied degrees of WIT within the scope of this study have no negative impact on the outcomes of allografts obtained laparoscopically or openly. As a result, rushing renal artery ligation and division and kidney extraction to reduce WIT at the price of hurting the kidney transplant and donor are not realistic. However, it is uncertain how long the WIT safety window will stay open. This discovery may enable more urologists to undertake LLDN without the previously considered detrimental impact of WIT in compared to OLDN.http://www.ijtonline.in/article.asp?issn=2212-0017;year=2023;volume=17;issue=4;spage=431;epage=435;aulast=Puniagraft functionlaparoscopic live-donor nephrectomylive donoropen live-donor nephrectomywarm ischemia time |
| spellingShingle | Sahil Punia Nripesh Sadasukhi Trilok Chand Sadasukhi Hotilal L Gupta Manish Gupta Ashish Sharma To compare the effect of warm ischemia time and its significance, if any - open versus laparoscopic donor nephrectomy Indian Journal of Transplantation graft function laparoscopic live-donor nephrectomy live donor open live-donor nephrectomy warm ischemia time |
| title | To compare the effect of warm ischemia time and its significance, if any - open versus laparoscopic donor nephrectomy |
| title_full | To compare the effect of warm ischemia time and its significance, if any - open versus laparoscopic donor nephrectomy |
| title_fullStr | To compare the effect of warm ischemia time and its significance, if any - open versus laparoscopic donor nephrectomy |
| title_full_unstemmed | To compare the effect of warm ischemia time and its significance, if any - open versus laparoscopic donor nephrectomy |
| title_short | To compare the effect of warm ischemia time and its significance, if any - open versus laparoscopic donor nephrectomy |
| title_sort | to compare the effect of warm ischemia time and its significance if any open versus laparoscopic donor nephrectomy |
| topic | graft function laparoscopic live-donor nephrectomy live donor open live-donor nephrectomy warm ischemia time |
| url | http://www.ijtonline.in/article.asp?issn=2212-0017;year=2023;volume=17;issue=4;spage=431;epage=435;aulast=Punia |
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