Intraovarian platelet-rich plasma: current status
Abstract Background The successful use of PRP in regenerative medicine has led investigators to study its effect in the treatment of conditions like decreased ovarian reserve, poor responders, and premature ovarian insufficiency. Objective To review the uses of intraovarian PRP in reproductive medic...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2021-08-01
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| Series: | Middle East Fertility Society Journal |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s43043-021-00077-0 |
| _version_ | 1828920044476694528 |
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| author | Aboubakr Mohamed Elnashar |
| author_facet | Aboubakr Mohamed Elnashar |
| author_sort | Aboubakr Mohamed Elnashar |
| collection | DOAJ |
| description | Abstract Background The successful use of PRP in regenerative medicine has led investigators to study its effect in the treatment of conditions like decreased ovarian reserve, poor responders, and premature ovarian insufficiency. Objective To review the uses of intraovarian PRP in reproductive medicine. Methods A literature search for English articles related to the uses of intraovarian PRP in reproductive medicine, including articles published in PubMed, from 2000 to April 2021. Results Seventeen studies: No RCT. Studies were classified according to indication. (1) For diminished ovarian reserve: 6 studies including 369 patients. (2). For poor responders: 3 case series studies including 41 patients with an improvement in ovarian response. (3) For premature ovarian insufficiency: 8 studies including 373 patients. Ovarian reserve markers were the outcome of all studies with conflicting results. LBR was not determined in the majority of studies. Conclusion Intraovarian PRP for diminished ovarian reserve, poor ovarian response, or POI is still experimental. Well-designed, large RCTS to confirm its efficacy and safety are required. |
| first_indexed | 2024-12-13T21:39:39Z |
| format | Article |
| id | doaj.art-592f56e0531b4d698d07e7be1d15e0dd |
| institution | Directory Open Access Journal |
| issn | 2090-3251 |
| language | English |
| last_indexed | 2024-12-13T21:39:39Z |
| publishDate | 2021-08-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | Middle East Fertility Society Journal |
| spelling | doaj.art-592f56e0531b4d698d07e7be1d15e0dd2022-12-21T23:30:35ZengSpringerOpenMiddle East Fertility Society Journal2090-32512021-08-012611510.1186/s43043-021-00077-0Intraovarian platelet-rich plasma: current statusAboubakr Mohamed Elnashar0Benha University HospitalAbstract Background The successful use of PRP in regenerative medicine has led investigators to study its effect in the treatment of conditions like decreased ovarian reserve, poor responders, and premature ovarian insufficiency. Objective To review the uses of intraovarian PRP in reproductive medicine. Methods A literature search for English articles related to the uses of intraovarian PRP in reproductive medicine, including articles published in PubMed, from 2000 to April 2021. Results Seventeen studies: No RCT. Studies were classified according to indication. (1) For diminished ovarian reserve: 6 studies including 369 patients. (2). For poor responders: 3 case series studies including 41 patients with an improvement in ovarian response. (3) For premature ovarian insufficiency: 8 studies including 373 patients. Ovarian reserve markers were the outcome of all studies with conflicting results. LBR was not determined in the majority of studies. Conclusion Intraovarian PRP for diminished ovarian reserve, poor ovarian response, or POI is still experimental. Well-designed, large RCTS to confirm its efficacy and safety are required.https://doi.org/10.1186/s43043-021-00077-0PRPICSIOvaryPlatelet-rich plasma |
| spellingShingle | Aboubakr Mohamed Elnashar Intraovarian platelet-rich plasma: current status Middle East Fertility Society Journal PRP ICSI Ovary Platelet-rich plasma |
| title | Intraovarian platelet-rich plasma: current status |
| title_full | Intraovarian platelet-rich plasma: current status |
| title_fullStr | Intraovarian platelet-rich plasma: current status |
| title_full_unstemmed | Intraovarian platelet-rich plasma: current status |
| title_short | Intraovarian platelet-rich plasma: current status |
| title_sort | intraovarian platelet rich plasma current status |
| topic | PRP ICSI Ovary Platelet-rich plasma |
| url | https://doi.org/10.1186/s43043-021-00077-0 |
| work_keys_str_mv | AT aboubakrmohamedelnashar intraovarianplateletrichplasmacurrentstatus |