Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing.

Rapid identification of genetic modifications in Bacillus anthracis using whole genome draft sequences generated by 454 pyrosequencing.

BACKGROUND: The anthrax letter attacks of 2001 highlighted the need for rapid identification of biothreat agents not only for epidemiological surveillance of the intentional outbreak but also for implementing appropriate countermeasures, such as antibiotic treatment, in a timely manner to prevent fu...

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Main Authors: Peter E Chen, Kristin M Willner, Amy Butani, Shakia Dorsey, Matroner George, Andrew Stewart, Shannon M Lentz, Christopher E Cook, Arya Akmal, Lance B Price, Paul S Keim, Alfred Mateczun, Trupti N Brahmbhatt, Kimberly A Bishop-Lilly, Michael E Zwick, Timothy D Read, Shanmuga Sozhamannan
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2928293?pdf=render

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