The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndrome
Introduction: Premenstrual syndrome (PMS) is one of the most common psychosomatic disorders in women which significantly affects their social quality of life. Some studies have demonstrated the effects of Salvia on some problems of menstruation. Therefore, this study was performed with aim to invest...
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| Format: | Article |
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Mashhad University of Medical Sciences
2017-12-01
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| Series: | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
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| Online Access: | https://ijogi.mums.ac.ir/article_10160_9947723b6d90c229d1b0cec0b7986bb7.pdf |
| _version_ | 1811223383304568832 |
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| author | Roghayeh Abdnezhad Masoumeh Simbar Zohreh Sheikhan Faraz Mojab Malihe Nasiri |
| author_facet | Roghayeh Abdnezhad Masoumeh Simbar Zohreh Sheikhan Faraz Mojab Malihe Nasiri |
| author_sort | Roghayeh Abdnezhad |
| collection | DOAJ |
| description | Introduction: Premenstrual syndrome (PMS) is one of the most common psychosomatic disorders in women which significantly affects their social quality of life. Some studies have demonstrated the effects of Salvia on some problems of menstruation. Therefore, this study was performed with aim to investigate the effects of Salvia extract on the symptoms of PMS.
Methods: This randomized, triple-blind, clinical trial study was conducted on 90 students living in the dormitories of Shahid Beheshti University of Medical Sciences in 2015. After diagnosis by the standard form of PMS diagnosis, the samples were randomly assigned to two groups. They were treated for two consecutive months, since the 21st day of menstruation till the 5th day of next menstrual cycle with 500 mg sage capsule or placebo once a day. Data collection tools were questionnaire and the form of daily status recording of the symptoms. Data was analyzed by SPSS software (version 20) and t-test, Chi-square, Mann-Whitney, and repeated measurements tests. P<0.05 was considered significant.
Results: Although there was a significant difference between the two groups of sage and placebo in terms of overall severity of premenstrual syndrome symptoms before treatment (P<0.001), but the difference between the mean reduction in the overall severity of symptoms after the first and second stages of treatment was significant and showed the greater effect of sage (P<0.001). There was a significant difference between the two groups in reducing the severity of emotional symptoms, and sage was more effective than placebo (P <0.001).
Conclusion: Sage extract reduces the severity of emotional symptoms of PMS; it is more effective than placebo. |
| first_indexed | 2024-04-12T08:32:04Z |
| format | Article |
| id | doaj.art-5936f238f71b47dfa38c16da94e3483c |
| institution | Directory Open Access Journal |
| issn | 1680-2993 2008-2363 |
| language | fas |
| last_indexed | 2024-04-12T08:32:04Z |
| publishDate | 2017-12-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān |
| spelling | doaj.art-5936f238f71b47dfa38c16da94e3483c2022-12-22T03:40:12ZfasMashhad University of Medical SciencesMajallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān1680-29932008-23632017-12-012010849410.22038/ijogi.2017.1016010160The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndromeRoghayeh Abdnezhad0Masoumeh Simbar1Zohreh Sheikhan2Faraz Mojab3Malihe Nasiri4M.Sc. student in Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Professor, Department of Midwifery and Reproductive Health, Reproductive Endocrinology Research Center, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Instructor, Department of Midwifery, School of Nursing and Midwifery, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Professor, Department of Pharmacognosy, School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.Assistant professor, Department of Biostatistics, School of Paramedicine, Shahid Beheshti University of Medical Science, Tehran, Iran.Introduction: Premenstrual syndrome (PMS) is one of the most common psychosomatic disorders in women which significantly affects their social quality of life. Some studies have demonstrated the effects of Salvia on some problems of menstruation. Therefore, this study was performed with aim to investigate the effects of Salvia extract on the symptoms of PMS. Methods: This randomized, triple-blind, clinical trial study was conducted on 90 students living in the dormitories of Shahid Beheshti University of Medical Sciences in 2015. After diagnosis by the standard form of PMS diagnosis, the samples were randomly assigned to two groups. They were treated for two consecutive months, since the 21st day of menstruation till the 5th day of next menstrual cycle with 500 mg sage capsule or placebo once a day. Data collection tools were questionnaire and the form of daily status recording of the symptoms. Data was analyzed by SPSS software (version 20) and t-test, Chi-square, Mann-Whitney, and repeated measurements tests. P<0.05 was considered significant. Results: Although there was a significant difference between the two groups of sage and placebo in terms of overall severity of premenstrual syndrome symptoms before treatment (P<0.001), but the difference between the mean reduction in the overall severity of symptoms after the first and second stages of treatment was significant and showed the greater effect of sage (P<0.001). There was a significant difference between the two groups in reducing the severity of emotional symptoms, and sage was more effective than placebo (P <0.001). Conclusion: Sage extract reduces the severity of emotional symptoms of PMS; it is more effective than placebo.https://ijogi.mums.ac.ir/article_10160_9947723b6d90c229d1b0cec0b7986bb7.pdfclinical trialemotional symptomspremenstrual syndromesage extract |
| spellingShingle | Roghayeh Abdnezhad Masoumeh Simbar Zohreh Sheikhan Faraz Mojab Malihe Nasiri The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndrome Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān clinical trial emotional symptoms premenstrual syndrome sage extract |
| title | The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndrome |
| title_full | The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndrome |
| title_fullStr | The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndrome |
| title_full_unstemmed | The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndrome |
| title_short | The effect of Salvia (Sage) extract on the emotional symptoms of premenstrual syndrome |
| title_sort | effect of salvia sage extract on the emotional symptoms of premenstrual syndrome |
| topic | clinical trial emotional symptoms premenstrual syndrome sage extract |
| url | https://ijogi.mums.ac.ir/article_10160_9947723b6d90c229d1b0cec0b7986bb7.pdf |
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