The Responses of Autophagy and Apoptosis to Oxidative Stress in Nucleus Pulposus Cells: Implications for Disc Degeneration

The Responses of Autophagy and Apoptosis to Oxidative Stress in Nucleus Pulposus Cells: Implications for Disc Degeneration

Background/Aims: Apoptosis and autophagy are two patterns of programmed cell death which play important roles in the intervertebral disc degeneration. Oxidative stress is an important factor for the induction of programmed cell death. However, the cellular reactions linking autophagy to apoptosis of...

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Bibliographic Details
Main Authors: Jiang-Wei Chen, Bin-Bin Ni, Bo Li, Yue-Hua Yang, Sheng-Dan Jiang, Lei-Sheng Jiang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2014-09-01
Series:Cellular Physiology and Biochemistry
Subjects:
Oxidative stress
Autophagy
Apoptosis
ERK
Nucleus pulposus cells
Online Access:http://www.karger.com/Article/FullText/366330

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