Anterior Cervical Decompression and Fusion Surgery for Cervical Spondylosis with Concomitant Tinnitus: A Multicenter Prospective Cohort Study
Objective Cervical spondylosis is often accompanied by tinnitus. Up to now, there is a lack of large samples and prospective studies to investigate the effect of anterior cervical decompression and fusion (ACDF) on tinnitus associate with cervical spondylosis. To this end, we performed a prospective...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-01-01
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| Series: | Orthopaedic Surgery |
| Subjects: | |
| Online Access: | https://doi.org/10.1111/os.13578 |
| _version_ | 1797954096888545280 |
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| author | Liang Yang Yongchao Li Xiaodong Pang Duanming Li Ye Wu Xiongsheng Chen Baogan Peng |
| author_facet | Liang Yang Yongchao Li Xiaodong Pang Duanming Li Ye Wu Xiongsheng Chen Baogan Peng |
| author_sort | Liang Yang |
| collection | DOAJ |
| description | Objective Cervical spondylosis is often accompanied by tinnitus. Up to now, there is a lack of large samples and prospective studies to investigate the effect of anterior cervical decompression and fusion (ACDF) on tinnitus associate with cervical spondylosis. To this end, we performed a prospective cohort study to assess the effectiveness of ACDF on the relief of tinnitus. Methods This was a multicenter, prospective, cohort clinical study. Between August 2017 and August 2018, 174 patients with cervical spondylosis accompanied by tinnitus were enrolled, with a follow‐up of 12 months. Among the 174 patients, 142 received anterior cervical surgery (surgery group) and 32 received conservative treatment (conservative group). The primary end point was the mean change in scores on the tinnitus functional index (TFI). The secondary end points included tinnitus loudness, modified Japanese orthopaedic association scores (mJOA) for spinal cord function, and visual analogue scale (VAS) for neck pain. All the above indexes were measured before treatments and at 1, 3, 6, and 12 months after treatments. One‐way analysis of variance and paired samples t‐test was adopted for statistical analysis. Results The TFI score was reduced immediately after cervical decompression surgery (from 54.7 ± 15.6 to 32.3 ± 12.5, P < 0.001) and this was sustained at 12 months (P < 0.001). The TFI score of the conservative group also decreased (from 53.9 ± 16.8 to 45.2 ± 13.6, P < 0.001), but the effect was not maintained at 12 months (P = 0.069). There was a significant improvement in tinnitus loudness (from 5.2 ± 1.6 to 2.6 ± 1.9, P < 0.001), mJOA (from 12.0 ± 1.6 to 14.2 ± 1.6, P < 0.001), and VAS for neck pain (from 58.5 ± 9.6 to 22.0 ± 16.4, P < 0.001) in the surgical group. Improvements in the surgical group were statistically significantly greater than that in the conservative group (P < 0.001). Conclusion This study indicates that anterior cervical surgery can relieve tinnitus in patients with cervical spondylosis and that tinnitus is an accompanying manifestation of cervical spondylosis. |
| first_indexed | 2024-04-10T23:12:11Z |
| format | Article |
| id | doaj.art-5939421143644f4d8798aa02af79f66a |
| institution | Directory Open Access Journal |
| issn | 1757-7853 1757-7861 |
| language | English |
| last_indexed | 2024-04-10T23:12:11Z |
| publishDate | 2023-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Orthopaedic Surgery |
| spelling | doaj.art-5939421143644f4d8798aa02af79f66a2023-01-13T04:29:06ZengWileyOrthopaedic Surgery1757-78531757-78612023-01-0115113314010.1111/os.13578Anterior Cervical Decompression and Fusion Surgery for Cervical Spondylosis with Concomitant Tinnitus: A Multicenter Prospective Cohort StudyLiang Yang0Yongchao Li1Xiaodong Pang2Duanming Li3Ye Wu4Xiongsheng Chen5Baogan Peng6Department of Orthopaedics Featured Medical Center of Chinese People's Armed Police Forces Tianjing ChinaDepartment of Orthopaedics The Third Medical Center of Chinese PLA General Hospital Beijing ChinaDepartment of Orthopaedics The Third Medical Center of Chinese PLA General Hospital Beijing ChinaDepartment of Orthopaedics The Third Medical Center of Chinese PLA General Hospital Beijing ChinaDepartment of Orthopaedics Beijing 304th Hospital Beijing ChinaSpine Center, Department of Orthopaedics Shanghai Changzheng Hospital, Second Affiliated Hospital of Naval Medical University Shanghai ChinaDepartment of Orthopaedics The Third Medical Center of Chinese PLA General Hospital Beijing ChinaObjective Cervical spondylosis is often accompanied by tinnitus. Up to now, there is a lack of large samples and prospective studies to investigate the effect of anterior cervical decompression and fusion (ACDF) on tinnitus associate with cervical spondylosis. To this end, we performed a prospective cohort study to assess the effectiveness of ACDF on the relief of tinnitus. Methods This was a multicenter, prospective, cohort clinical study. Between August 2017 and August 2018, 174 patients with cervical spondylosis accompanied by tinnitus were enrolled, with a follow‐up of 12 months. Among the 174 patients, 142 received anterior cervical surgery (surgery group) and 32 received conservative treatment (conservative group). The primary end point was the mean change in scores on the tinnitus functional index (TFI). The secondary end points included tinnitus loudness, modified Japanese orthopaedic association scores (mJOA) for spinal cord function, and visual analogue scale (VAS) for neck pain. All the above indexes were measured before treatments and at 1, 3, 6, and 12 months after treatments. One‐way analysis of variance and paired samples t‐test was adopted for statistical analysis. Results The TFI score was reduced immediately after cervical decompression surgery (from 54.7 ± 15.6 to 32.3 ± 12.5, P < 0.001) and this was sustained at 12 months (P < 0.001). The TFI score of the conservative group also decreased (from 53.9 ± 16.8 to 45.2 ± 13.6, P < 0.001), but the effect was not maintained at 12 months (P = 0.069). There was a significant improvement in tinnitus loudness (from 5.2 ± 1.6 to 2.6 ± 1.9, P < 0.001), mJOA (from 12.0 ± 1.6 to 14.2 ± 1.6, P < 0.001), and VAS for neck pain (from 58.5 ± 9.6 to 22.0 ± 16.4, P < 0.001) in the surgical group. Improvements in the surgical group were statistically significantly greater than that in the conservative group (P < 0.001). Conclusion This study indicates that anterior cervical surgery can relieve tinnitus in patients with cervical spondylosis and that tinnitus is an accompanying manifestation of cervical spondylosis.https://doi.org/10.1111/os.13578Anterior cervical decompression and fusionCervical disc degenerationCervical somatosensoryCervical spondylosisTinnitus |
| spellingShingle | Liang Yang Yongchao Li Xiaodong Pang Duanming Li Ye Wu Xiongsheng Chen Baogan Peng Anterior Cervical Decompression and Fusion Surgery for Cervical Spondylosis with Concomitant Tinnitus: A Multicenter Prospective Cohort Study Orthopaedic Surgery Anterior cervical decompression and fusion Cervical disc degeneration Cervical somatosensory Cervical spondylosis Tinnitus |
| title | Anterior Cervical Decompression and Fusion Surgery for Cervical Spondylosis with Concomitant Tinnitus: A Multicenter Prospective Cohort Study |
| title_full | Anterior Cervical Decompression and Fusion Surgery for Cervical Spondylosis with Concomitant Tinnitus: A Multicenter Prospective Cohort Study |
| title_fullStr | Anterior Cervical Decompression and Fusion Surgery for Cervical Spondylosis with Concomitant Tinnitus: A Multicenter Prospective Cohort Study |
| title_full_unstemmed | Anterior Cervical Decompression and Fusion Surgery for Cervical Spondylosis with Concomitant Tinnitus: A Multicenter Prospective Cohort Study |
| title_short | Anterior Cervical Decompression and Fusion Surgery for Cervical Spondylosis with Concomitant Tinnitus: A Multicenter Prospective Cohort Study |
| title_sort | anterior cervical decompression and fusion surgery for cervical spondylosis with concomitant tinnitus a multicenter prospective cohort study |
| topic | Anterior cervical decompression and fusion Cervical disc degeneration Cervical somatosensory Cervical spondylosis Tinnitus |
| url | https://doi.org/10.1111/os.13578 |
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