Differential Modulation of miR-122 Transcription by TGFβ1/BMP6: Implications for Nonresolving Inflammation and Hepatocarcinogenesis

Differential Modulation of miR-122 Transcription by TGFβ1/BMP6: Implications for Nonresolving Inflammation and Hepatocarcinogenesis

Chronic inflammation is widely recognized as a significant factor that promotes and worsens the development of malignancies, including hepatocellular carcinoma. This study aimed to explore the potential role of microRNAs in inflammation-associated nonresolving hepatocarcinogenesis. By conducting a c...

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Bibliographic Details
Main Authors: Martha Paluschinski, Claus Kordes, Mihael Vucur, Veronika Buettner, Christoph Roderburg, Haifeng C. Xu, Prashant V. Shinte, Philipp A. Lang, Tom Luedde, Mirco Castoldi
Format: Article
Language:English
Published: MDPI AG 2023-07-01
Series:Cells
Subjects:
miR-122
inflammation
liver cancer
TGFβ1
BMP6
Smad4
Online Access:https://www.mdpi.com/2073-4409/12/15/1955

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