Non-Hodgkin's lymphoma-associated pleural effusion misdiagnosed as tubercular pleural effusion
Adenosine deaminase (ADA) in the pleural fluid has high sensitivity and specificity for diagnosing tubercular pleuritis. ADA level of more than 40 IU/L in a lymphocytic and exudative effusion is suggestive of tubercular etiology in clinical practice. Antitubercular chemotherapy is often instituted w...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2023-01-01
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| Series: | Journal of Advanced Lung Health |
| Subjects: | |
| Online Access: | http://www.jalh.org/article.asp?issn=2772-7165;year=2023;volume=3;issue=3;spage=108;epage=112;aulast=Mallik |
| _version_ | 1797738657052884992 |
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| author | Sonali Mallik Ananda Datta Amanpreet Kaur Swagatika Samal |
| author_facet | Sonali Mallik Ananda Datta Amanpreet Kaur Swagatika Samal |
| author_sort | Sonali Mallik |
| collection | DOAJ |
| description | Adenosine deaminase (ADA) in the pleural fluid has high sensitivity and specificity for diagnosing tubercular pleuritis. ADA level of more than 40 IU/L in a lymphocytic and exudative effusion is suggestive of tubercular etiology in clinical practice. Antitubercular chemotherapy is often instituted without further histopathological or microbiological confirmation, especially in tuberculosis (TB)-endemic countries. Lymphoma is another important cause of elevated ADA levels in pleural fluid. Hence, in the absence of tissue diagnosis, lymphoma is often wrongly labeled as TB based on fluid characteristics. Here, we present a case of non-Hodgkin lymphoma with right-side pleural effusion who was initially misdiagnosed to have TB based on pleural fluid analysis. |
| first_indexed | 2024-03-12T13:47:00Z |
| format | Article |
| id | doaj.art-594a24d100b340d0987a512c1f81ac0b |
| institution | Directory Open Access Journal |
| issn | 2772-7165 2772-7173 |
| language | English |
| last_indexed | 2024-03-12T13:47:00Z |
| publishDate | 2023-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Journal of Advanced Lung Health |
| spelling | doaj.art-594a24d100b340d0987a512c1f81ac0b2023-08-23T08:56:11ZengWolters Kluwer Medknow PublicationsJournal of Advanced Lung Health2772-71652772-71732023-01-013310811210.4103/jalh.jalh_5_23Non-Hodgkin's lymphoma-associated pleural effusion misdiagnosed as tubercular pleural effusionSonali MallikAnanda DattaAmanpreet KaurSwagatika SamalAdenosine deaminase (ADA) in the pleural fluid has high sensitivity and specificity for diagnosing tubercular pleuritis. ADA level of more than 40 IU/L in a lymphocytic and exudative effusion is suggestive of tubercular etiology in clinical practice. Antitubercular chemotherapy is often instituted without further histopathological or microbiological confirmation, especially in tuberculosis (TB)-endemic countries. Lymphoma is another important cause of elevated ADA levels in pleural fluid. Hence, in the absence of tissue diagnosis, lymphoma is often wrongly labeled as TB based on fluid characteristics. Here, we present a case of non-Hodgkin lymphoma with right-side pleural effusion who was initially misdiagnosed to have TB based on pleural fluid analysis.http://www.jalh.org/article.asp?issn=2772-7165;year=2023;volume=3;issue=3;spage=108;epage=112;aulast=Mallikmisdiagnosisnon-hodgkin lymphomapleural effusion |
| spellingShingle | Sonali Mallik Ananda Datta Amanpreet Kaur Swagatika Samal Non-Hodgkin's lymphoma-associated pleural effusion misdiagnosed as tubercular pleural effusion Journal of Advanced Lung Health misdiagnosis non-hodgkin lymphoma pleural effusion |
| title | Non-Hodgkin's lymphoma-associated pleural effusion misdiagnosed as tubercular pleural effusion |
| title_full | Non-Hodgkin's lymphoma-associated pleural effusion misdiagnosed as tubercular pleural effusion |
| title_fullStr | Non-Hodgkin's lymphoma-associated pleural effusion misdiagnosed as tubercular pleural effusion |
| title_full_unstemmed | Non-Hodgkin's lymphoma-associated pleural effusion misdiagnosed as tubercular pleural effusion |
| title_short | Non-Hodgkin's lymphoma-associated pleural effusion misdiagnosed as tubercular pleural effusion |
| title_sort | non hodgkin s lymphoma associated pleural effusion misdiagnosed as tubercular pleural effusion |
| topic | misdiagnosis non-hodgkin lymphoma pleural effusion |
| url | http://www.jalh.org/article.asp?issn=2772-7165;year=2023;volume=3;issue=3;spage=108;epage=112;aulast=Mallik |
| work_keys_str_mv | AT sonalimallik nonhodgkinslymphomaassociatedpleuraleffusionmisdiagnosedastubercularpleuraleffusion AT anandadatta nonhodgkinslymphomaassociatedpleuraleffusionmisdiagnosedastubercularpleuraleffusion AT amanpreetkaur nonhodgkinslymphomaassociatedpleuraleffusionmisdiagnosedastubercularpleuraleffusion AT swagatikasamal nonhodgkinslymphomaassociatedpleuraleffusionmisdiagnosedastubercularpleuraleffusion |