Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case Report
Although Candida albicans remains the predominant species causing Blood Stream Infection (BSI), recent studies have demonstrated an emergence of Non-albicans Candida spp (NAC), such as C. glabrata, C. papapsilosis and C. krusei. Candida krusei are yeast-like microorganisms which may colonise the hum...
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| Format: | Article |
| Language: | English |
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JCDR Research and Publications Private Limited
2020-05-01
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| Series: | Journal of Clinical and Diagnostic Research |
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| Online Access: | https://jcdr.net/articles/PDF/13724/44269_CE[Ra1]_F(KM)_PF1(AG_SHU)_PFA(KM)_PB(AG_SL)_PN(SL).pdf |
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| author | Aroop Mohanty Suneeta Meena Uttam Kumar Nath Sudeep Vaniyath Neelam Kaistha |
| author_facet | Aroop Mohanty Suneeta Meena Uttam Kumar Nath Sudeep Vaniyath Neelam Kaistha |
| author_sort | Aroop Mohanty |
| collection | DOAJ |
| description | Although Candida albicans remains the predominant species causing Blood Stream Infection (BSI), recent studies have demonstrated an emergence of Non-albicans Candida spp (NAC), such as C. glabrata, C. papapsilosis and C. krusei. Candida krusei are yeast-like microorganisms which may colonise the human skin, respiratory or gastrointestinal tract but can cause lethal infections especially in immunocompromised patients. Hereby, author’s report a case of 10-year-old male with T-cell Acute Lymphocytic Leukaemia (ALL) who reported with fever and non-productive cough caused by Candida krusei. Direct gram stain from blood culture and germ tube test was performed. Further, the isolate was initially misidentified by Matrix Assisted Laser Desorption/Ionisation Time of Flight Mass Spectrometry (MALDI-TOF MS) as Trichosporon ovoides which was later identified by molecular sequencing as Candida krusei. |
| first_indexed | 2024-12-21T19:11:17Z |
| format | Article |
| id | doaj.art-594ccae488ed49b998c7d654c53a1dff |
| institution | Directory Open Access Journal |
| issn | 2249-782X 0973-709X |
| language | English |
| last_indexed | 2024-12-21T19:11:17Z |
| publishDate | 2020-05-01 |
| publisher | JCDR Research and Publications Private Limited |
| record_format | Article |
| series | Journal of Clinical and Diagnostic Research |
| spelling | doaj.art-594ccae488ed49b998c7d654c53a1dff2022-12-21T18:53:11ZengJCDR Research and Publications Private LimitedJournal of Clinical and Diagnostic Research2249-782X0973-709X2020-05-01145DD01DD0310.7860/JCDR/2020/44269.13724Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case ReportAroop Mohanty0Suneeta Meena1Uttam Kumar Nath2Sudeep Vaniyath3Neelam Kaistha4Assistant Professor, Department of Microbiology, AIIMS, Rishikesh, Uttarakhand, India.Assistant Professor, Department of Laboratory Medicine, AIIMS, New Delhi, India.Additional Professor, Department of Medical Oncology and Haematology, AIIMS, Rishikesh, Uttarakhand, India.Senior Resident, Department of Medical Oncology and Haematology, AIIMS, Rishikesh, Uttarakhand, India.Professor, Department of Microbiology, AIIMS, Rishikesh, Uttarakhand, India.Although Candida albicans remains the predominant species causing Blood Stream Infection (BSI), recent studies have demonstrated an emergence of Non-albicans Candida spp (NAC), such as C. glabrata, C. papapsilosis and C. krusei. Candida krusei are yeast-like microorganisms which may colonise the human skin, respiratory or gastrointestinal tract but can cause lethal infections especially in immunocompromised patients. Hereby, author’s report a case of 10-year-old male with T-cell Acute Lymphocytic Leukaemia (ALL) who reported with fever and non-productive cough caused by Candida krusei. Direct gram stain from blood culture and germ tube test was performed. Further, the isolate was initially misidentified by Matrix Assisted Laser Desorption/Ionisation Time of Flight Mass Spectrometry (MALDI-TOF MS) as Trichosporon ovoides which was later identified by molecular sequencing as Candida krusei.https://jcdr.net/articles/PDF/13724/44269_CE[Ra1]_F(KM)_PF1(AG_SHU)_PFA(KM)_PB(AG_SL)_PN(SL).pdfcandida speciesfungemiahaematological malignancy |
| spellingShingle | Aroop Mohanty Suneeta Meena Uttam Kumar Nath Sudeep Vaniyath Neelam Kaistha Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case Report Journal of Clinical and Diagnostic Research candida species fungemia haematological malignancy |
| title | Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case Report |
| title_full | Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case Report |
| title_fullStr | Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case Report |
| title_full_unstemmed | Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case Report |
| title_short | Candida krusei Infection in an Acute Lymphocytic Leukaemia Patient: A Case Report |
| title_sort | candida krusei infection in an acute lymphocytic leukaemia patient a case report |
| topic | candida species fungemia haematological malignancy |
| url | https://jcdr.net/articles/PDF/13724/44269_CE[Ra1]_F(KM)_PF1(AG_SHU)_PFA(KM)_PB(AG_SL)_PN(SL).pdf |
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