Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria
Whole cells of hydrocarbon-degrading bacteria, isolated from polluted sediments in the Santos Estuary (Baixada Santista, São Paulo, Brazil), were able to catalyse oxidoreduction reactions with various substituted phenylethanols and acetophenones as substrates. A number of substituted phenylethanols...
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| Format: | Article |
| Language: | English |
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University of Zagreb Faculty of Food Technology and Biotechnology
2008-01-01
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| Series: | Food Technology and Biotechnology |
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| Online Access: | http://hrcak.srce.hr/file/48119 |
| _version_ | 1797428167056556032 |
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| author | Edna Kagohara Vivian Helena Pellizari João Valdir Comasseto Leandro Helgueira Andrade André Luiz Meleiro Porto |
| author_facet | Edna Kagohara Vivian Helena Pellizari João Valdir Comasseto Leandro Helgueira Andrade André Luiz Meleiro Porto |
| author_sort | Edna Kagohara |
| collection | DOAJ |
| description | Whole cells of hydrocarbon-degrading bacteria, isolated from polluted sediments in the Santos Estuary (Baixada Santista, São Paulo, Brazil), were able to catalyse oxidoreduction reactions with various substituted phenylethanols and acetophenones as substrates. A number of substituted phenylethanols were formed with high (>99 %) enantiomeric excess. The results of microbial oxidation of phenylethanols 2, 3, 5–7 by Acinetobacter sp. 6.4T and the reduction of acetophenones 1a–6a by Serratia marcescens 5.4T showed that the bacteria used as biocatalysts in this study present significant potential for exploitation in biotechnological processes. The reduction of prochiral acetophenones by Serratia marcescens 3.5T yielded optically active alcohols with 90–99 % enantiomeric excess, and Acinetobacter sp. 6.4T is a potential biocatalyst for the oxidation of alcohols. |
| first_indexed | 2024-03-09T08:55:06Z |
| format | Article |
| id | doaj.art-594cd2e2cd5147e0a9d3b3a0b3da48ee |
| institution | Directory Open Access Journal |
| issn | 1330-9862 1334-2606 |
| language | English |
| last_indexed | 2024-03-09T08:55:06Z |
| publishDate | 2008-01-01 |
| publisher | University of Zagreb Faculty of Food Technology and Biotechnology |
| record_format | Article |
| series | Food Technology and Biotechnology |
| spelling | doaj.art-594cd2e2cd5147e0a9d3b3a0b3da48ee2023-12-02T13:24:45ZengUniversity of Zagreb Faculty of Food Technology and BiotechnologyFood Technology and Biotechnology1330-98621334-26062008-01-01464381387Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental BacteriaEdna Kagohara0Vivian Helena Pellizari1João Valdir Comasseto2Leandro Helgueira Andrade3André Luiz Meleiro Porto4Laboratory of Organic Chemistry and Biocatalysis, Institute of Chemistry, University of São Paulo, São Paulo, SP, BrazilLaboratory of Environmental Microbiology, Department of Microbiology, University of São Paulo, São Paulo, SP, BrazilLaboratory of Organic Chemistry and Biocatalysis, Institute of Chemistry, University of São Paulo, São Paulo, SP, BrazilLaboratory of Organic Chemistry and Biocatalysis, Institute of Chemistry, University of São Paulo, São Paulo, SP, BrazilInstitute of Chemistry of São Carlos, University of São Paulo, Av. Trabalhador São-Carlense 400, CEP 13566-590 São Carlos, SP, BrazilWhole cells of hydrocarbon-degrading bacteria, isolated from polluted sediments in the Santos Estuary (Baixada Santista, São Paulo, Brazil), were able to catalyse oxidoreduction reactions with various substituted phenylethanols and acetophenones as substrates. A number of substituted phenylethanols were formed with high (>99 %) enantiomeric excess. The results of microbial oxidation of phenylethanols 2, 3, 5–7 by Acinetobacter sp. 6.4T and the reduction of acetophenones 1a–6a by Serratia marcescens 5.4T showed that the bacteria used as biocatalysts in this study present significant potential for exploitation in biotechnological processes. The reduction of prochiral acetophenones by Serratia marcescens 3.5T yielded optically active alcohols with 90–99 % enantiomeric excess, and Acinetobacter sp. 6.4T is a potential biocatalyst for the oxidation of alcohols.http://hrcak.srce.hr/file/48119oxidoreductionbacteriachiral alcoholsbiotransformations |
| spellingShingle | Edna Kagohara Vivian Helena Pellizari João Valdir Comasseto Leandro Helgueira Andrade André Luiz Meleiro Porto Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria Food Technology and Biotechnology oxidoreduction bacteria chiral alcohols biotransformations |
| title | Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria |
| title_full | Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria |
| title_fullStr | Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria |
| title_full_unstemmed | Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria |
| title_short | Biotransformations of Substituted Phenylethanols and Acetophenones by Environmental Bacteria |
| title_sort | biotransformations of substituted phenylethanols and acetophenones by environmental bacteria |
| topic | oxidoreduction bacteria chiral alcohols biotransformations |
| url | http://hrcak.srce.hr/file/48119 |
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