The Caenorhabditis elegans GATA factor ELT-1 works through the cell proliferation regulator BRO-1 and the Fusogen EFF-1 to maintain the seam stem-like fate.
Seam cells in Caenorhabditis elegans provide a paradigm for the stem cell mode of division, with the ability to both self-renew and produce daughters that differentiate. The transcription factor RNT-1 and its DNA binding partner BRO-1 (homologues of the mammalian cancer-associated stem cell regulato...
Main Authors: | Charles Brabin, Peter J Appleford, Alison Woollard |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2011-08-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC3150447?pdf=render |
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