Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis
Background/Aims: Dietary factors can aggravate the symptoms of irritable bowel syndrome (IBS). Many IBS patients try restrictive diets to relieve their symptoms, but the types of diets with an exacerbating factor are unknown. Therefore, this paper reports the results of a systematic review and netwo...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Jin Publishing & Printing Co.
2022-07-01
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| Series: | The Korean Journal of Gastroenterology |
| Subjects: | |
| Online Access: | https://www.kjg.or.kr/journal/view.html?uid=5833&vmd=Full |
| _version_ | 1797272351043223552 |
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| author | Seung Jung Yu Hong Sub Lee Hyeon Jeong Gung Ju Seok Kim Ki Bae Kim Yong Hwan Kwon Jae Hak Kim Hoon Sup Koo Hyun-Deok Shin Han Byul Lee Jeehyoung Kim Hye-Won Park IBS Research Study Group of the Korean Society of Neurogastroenterology and Motility |
| author_facet | Seung Jung Yu Hong Sub Lee Hyeon Jeong Gung Ju Seok Kim Ki Bae Kim Yong Hwan Kwon Jae Hak Kim Hoon Sup Koo Hyun-Deok Shin Han Byul Lee Jeehyoung Kim Hye-Won Park IBS Research Study Group of the Korean Society of Neurogastroenterology and Motility |
| author_sort | Seung Jung Yu |
| collection | DOAJ |
| description | Background/Aims: Dietary factors can aggravate the symptoms of irritable bowel syndrome (IBS). Many IBS patients try restrictive diets to relieve their symptoms, but the types of diets with an exacerbating factor are unknown. Therefore, this paper reports the results of a systematic review and network meta-analysis of randomized-controlled trials (RCTs) reviewing the efficacy of food restriction diets in IBS.
Methods: The MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Clinicaltrials.gov databases were searched until July 21, 2021, to retrieve RCTs assessing the efficacy of restriction diets in adults with IBS. Two independent reviewers performed the eligibility assessment and data abstraction. RCTs that evaluated a restriction diet versus a control diet and assessed the improvement in global IBS symptoms were included. These trials reported a dichotomous assessment of the overall response to therapy.
Results: A total of 1,949 citations were identified. After full-text screening, 14 RCTs were considered eligible for the systematic review and network meta-analysis. A starch- and sucrose-reduced diet and a diet with low-fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) showed significantly better results than a usual diet. Symptom flare-ups in patients on a gluten- free diet were also significantly lower than in those on high-gluten diets.
Conclusions: These findings showed that the starch- and sucrose-reduced, low FODMAP, and gluten-free diets had superior effects in reducing IBS symptoms. Further studies, including head-to-head trials will be needed to establish the effectiveness of dietary restrictions on IBS symptoms. |
| first_indexed | 2024-03-07T14:27:04Z |
| format | Article |
| id | doaj.art-594fb74ae8754a228f06f049f640c452 |
| institution | Directory Open Access Journal |
| issn | 1598-9992 2233-6869 |
| language | English |
| last_indexed | 2024-03-07T14:27:04Z |
| publishDate | 2022-07-01 |
| publisher | Jin Publishing & Printing Co. |
| record_format | Article |
| series | The Korean Journal of Gastroenterology |
| spelling | doaj.art-594fb74ae8754a228f06f049f640c4522024-03-06T06:07:05ZengJin Publishing & Printing Co.The Korean Journal of Gastroenterology1598-99922233-68692022-07-0180161610.4166/kjg.2022.014Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysisSeung Jung Yu0Hong Sub Lee1https://orcid.org/0000-0002-2962-0209Hyeon Jeong Gung2Ju Seok Kim3Ki Bae Kim4Yong Hwan Kwon5Jae Hak Kim6Hoon Sup Koo7Hyun-Deok Shin8Han Byul Lee9Jeehyoung Kim10Hye-Won Park11IBS Research Study Group of the Korean Society of Neurogastroenterology and MotilityDepartment of Internal Medicine, Inje University Busan Paik Hospital, Busan, KoreaDepartment of Internal Medicine, Inje University Busan Paik Hospital, Busan, KoreaDepartment of Internal Medicine, Soonchunhyang University Hospital Bucheon, Bucheon, KoreaDepartment of Internal Medicine, Chungnam National University College of Medicine, Daejeon, KoreaDepartment of Internal Medicine, Chungbuk National University Hospital, Cheongju, KoreaDepartment of Internal Medicine, Kyungpook National University Hospital, Daegu, KoreaDepartment of Internal Medicine, Dongguk University College of Medicine, Goyang, KoreaDepartment of Internal Medicine, Konyang University Hospital, Daejeon, KoreaDepartment of Internal Medicine, Dankook University Hospital, Cheonan, KoreaDepartment of Public Health, Ajou University Graduate School of Public Health, Suwon, KoreaDepartment of Orthopedic Surgery, Seoul Sacred Heart General Hospital, Seoul, KoreaDepartment of Internal Medicine, Inje University Medical Library, Busan, KoreaBackground/Aims: Dietary factors can aggravate the symptoms of irritable bowel syndrome (IBS). Many IBS patients try restrictive diets to relieve their symptoms, but the types of diets with an exacerbating factor are unknown. Therefore, this paper reports the results of a systematic review and network meta-analysis of randomized-controlled trials (RCTs) reviewing the efficacy of food restriction diets in IBS. Methods: The MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials, and Clinicaltrials.gov databases were searched until July 21, 2021, to retrieve RCTs assessing the efficacy of restriction diets in adults with IBS. Two independent reviewers performed the eligibility assessment and data abstraction. RCTs that evaluated a restriction diet versus a control diet and assessed the improvement in global IBS symptoms were included. These trials reported a dichotomous assessment of the overall response to therapy. Results: A total of 1,949 citations were identified. After full-text screening, 14 RCTs were considered eligible for the systematic review and network meta-analysis. A starch- and sucrose-reduced diet and a diet with low-fermentable oligosaccharides, disaccharides, monosaccharides, and polyols (FODMAPs) showed significantly better results than a usual diet. Symptom flare-ups in patients on a gluten- free diet were also significantly lower than in those on high-gluten diets. Conclusions: These findings showed that the starch- and sucrose-reduced, low FODMAP, and gluten-free diets had superior effects in reducing IBS symptoms. Further studies, including head-to-head trials will be needed to establish the effectiveness of dietary restrictions on IBS symptoms.https://www.kjg.or.kr/journal/view.html?uid=5833&vmd=Fullirritable bowel syndromenetwork meta-analysissystematic reviewrestrictive diet therapy |
| spellingShingle | Seung Jung Yu Hong Sub Lee Hyeon Jeong Gung Ju Seok Kim Ki Bae Kim Yong Hwan Kwon Jae Hak Kim Hoon Sup Koo Hyun-Deok Shin Han Byul Lee Jeehyoung Kim Hye-Won Park IBS Research Study Group of the Korean Society of Neurogastroenterology and Motility Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis The Korean Journal of Gastroenterology irritable bowel syndrome network meta-analysis systematic review restrictive diet therapy |
| title | Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis |
| title_full | Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis |
| title_fullStr | Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis |
| title_full_unstemmed | Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis |
| title_short | Efficacy of a Restrictive Diet in Irritable Bowel Syndrome: A Systematic Review and Network Meta-analysis |
| title_sort | efficacy of a restrictive diet in irritable bowel syndrome a systematic review and network meta analysis |
| topic | irritable bowel syndrome network meta-analysis systematic review restrictive diet therapy |
| url | https://www.kjg.or.kr/journal/view.html?uid=5833&vmd=Full |
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