The Gengnianchun recipe attenuates insulin resistance-induced diminished ovarian reserve through inhibiting the senescence of granulosa cells

The Gengnianchun recipe attenuates insulin resistance-induced diminished ovarian reserve through inhibiting the senescence of granulosa cells

IntroductionInsulin resistance (IR) is found in patients with polycystic ovary syndrome (PCOS), but the effects and mechanisms of IR on diminished ovarian reserve (DOR) remain unclear. This study set out to investigate the effects of IR on ovarian reserve; to explore the effects of high concentratio...

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Bibliographic Details
Main Authors: Hongna Gao, Lingyun Gao, Yanqiu Rao, Laidi Qian, Mingqing Li, Wenjun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Endocrinology
Subjects:
insulin resistance
diminished ovarian reserve
granulosa cells
cell senescence
traditional Chinese medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2023.1133280/full

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