Aging Regulated Through a Stability Model of Insulin/Insulin Growth Factor Receptor Function

Aging Regulated Through a Stability Model of Insulin/Insulin Growth Factor Receptor Function

Mutations of the insulin-like receptor in Drosophila extend lifespan. New research suggests this receptor operates in two modes. The first extends lifespan while slowing reproduction and reducing growth. The second strongly extends lifespan without impairing growth or reproduction; it confers longev...

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Bibliographic Details
Main Author: Marc Tatar
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Endocrinology
Subjects:
aging
Drosophila
insulin receptor
insulin
IGF
reproduction
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.649880/full

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