Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study
Objectives: Data about long-term mortality of Indian patients following acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are scant. We set out to study the 2-year mortality in north Indian patients following discharge after AECOPD. Materials and Methods: One hundred and fifty-one...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2017-01-01
|
| Series: | Lung India |
| Subjects: | |
| Online Access: | http://www.lungindia.com/article.asp?issn=0970-2113;year=2017;volume=34;issue=6;spage=511;epage=516;aulast=Koul |
| _version_ | 1819169680322985984 |
|---|---|
| author | Parvaiz A Koul Hilal A Dar Rafi A Jan Sanaullah Shah Umar Hafiz Khan |
| author_facet | Parvaiz A Koul Hilal A Dar Rafi A Jan Sanaullah Shah Umar Hafiz Khan |
| author_sort | Parvaiz A Koul |
| collection | DOAJ |
| description | Objectives: Data about long-term mortality of Indian patients following acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are scant. We set out to study the 2-year mortality in north Indian patients following discharge after AECOPD. Materials and Methods: One hundred and fifty-one (96 male) patients admitted for AECOPD and discharged were followed for 2 years at 3, 6, 12, 18, and 24 months for mortality. Statistical analysis was performed to identify risk factors associated with mortality. Results: Sixty (39.7%) of the 151 recruited died during the 24 months of follow-up, 30 (19.8%) at 3-month, 43 (28.5%) at 6-month, 49 (32.4%) at 1-year, 55 (36.4%) at 18-month, and 60 (39.7%) at 2 years. There was no mortality in Global Initiative for Chronic Obstructive Lung Disease (GOLD) Stage I (0 of 6 cases), whereas it was 12.3% (n = 8 of 65 patients) in GOLD Stage II, 41.7% (n = 15 of 36 cases), in GOLD Stage III, and 84.1% (n = 37 of 4 cases), of patients with GOLD Stage IV. Mortality was associated with 6-min walk distance, oxygen saturation, low body mass index, history of congestive heart failure, and St. George Respiratory Questionnaire score. Conclusion: Indian patients discharged after AECOPD have a high 2-year mortality. Measures to reduce the frequency of exacerbations need to be routinely adopted in patients with COPD. |
| first_indexed | 2024-12-22T19:23:21Z |
| format | Article |
| id | doaj.art-59544278259f4e90a506540082451cdc |
| institution | Directory Open Access Journal |
| issn | 0970-2113 0974-598X |
| language | English |
| last_indexed | 2024-12-22T19:23:21Z |
| publishDate | 2017-01-01 |
| publisher | Wolters Kluwer Medknow Publications |
| record_format | Article |
| series | Lung India |
| spelling | doaj.art-59544278259f4e90a506540082451cdc2022-12-21T18:15:19ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2017-01-0134651151610.4103/lungindia.lungindia_41_17Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian studyParvaiz A KoulHilal A DarRafi A JanSanaullah ShahUmar Hafiz KhanObjectives: Data about long-term mortality of Indian patients following acute exacerbation of chronic obstructive pulmonary disease (AECOPD) are scant. We set out to study the 2-year mortality in north Indian patients following discharge after AECOPD. Materials and Methods: One hundred and fifty-one (96 male) patients admitted for AECOPD and discharged were followed for 2 years at 3, 6, 12, 18, and 24 months for mortality. Statistical analysis was performed to identify risk factors associated with mortality. Results: Sixty (39.7%) of the 151 recruited died during the 24 months of follow-up, 30 (19.8%) at 3-month, 43 (28.5%) at 6-month, 49 (32.4%) at 1-year, 55 (36.4%) at 18-month, and 60 (39.7%) at 2 years. There was no mortality in Global Initiative for Chronic Obstructive Lung Disease (GOLD) Stage I (0 of 6 cases), whereas it was 12.3% (n = 8 of 65 patients) in GOLD Stage II, 41.7% (n = 15 of 36 cases), in GOLD Stage III, and 84.1% (n = 37 of 4 cases), of patients with GOLD Stage IV. Mortality was associated with 6-min walk distance, oxygen saturation, low body mass index, history of congestive heart failure, and St. George Respiratory Questionnaire score. Conclusion: Indian patients discharged after AECOPD have a high 2-year mortality. Measures to reduce the frequency of exacerbations need to be routinely adopted in patients with COPD.http://www.lungindia.com/article.asp?issn=0970-2113;year=2017;volume=34;issue=6;spage=511;epage=516;aulast=KoulAcute exacerbationchronic obstructive pulmonary diseaseGOLDmortality |
| spellingShingle | Parvaiz A Koul Hilal A Dar Rafi A Jan Sanaullah Shah Umar Hafiz Khan Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study Lung India Acute exacerbation chronic obstructive pulmonary disease GOLD mortality |
| title | Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study |
| title_full | Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study |
| title_fullStr | Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study |
| title_full_unstemmed | Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study |
| title_short | Two-year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease: A North Indian study |
| title_sort | two year mortality in survivors of acute exacerbations of chronic obstructive pulmonary disease a north indian study |
| topic | Acute exacerbation chronic obstructive pulmonary disease GOLD mortality |
| url | http://www.lungindia.com/article.asp?issn=0970-2113;year=2017;volume=34;issue=6;spage=511;epage=516;aulast=Koul |
| work_keys_str_mv | AT parvaizakoul twoyearmortalityinsurvivorsofacuteexacerbationsofchronicobstructivepulmonarydiseaseanorthindianstudy AT hilaladar twoyearmortalityinsurvivorsofacuteexacerbationsofchronicobstructivepulmonarydiseaseanorthindianstudy AT rafiajan twoyearmortalityinsurvivorsofacuteexacerbationsofchronicobstructivepulmonarydiseaseanorthindianstudy AT sanaullahshah twoyearmortalityinsurvivorsofacuteexacerbationsofchronicobstructivepulmonarydiseaseanorthindianstudy AT umarhafizkhan twoyearmortalityinsurvivorsofacuteexacerbationsofchronicobstructivepulmonarydiseaseanorthindianstudy |