Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation

Effect of Different Molecular Weights of Polyacrylic Acid on Rat Lung Following Intratracheal Instillation

Background: We conducted intratracheal instillations of different molecular weights of polyacrylic acid (PAA) into rats in order to examine what kinds of physicochemical characteristics of acrylic acid-based polymer affect responses in the lung. Methods: F344 rats were intratracheally exposed to a h...

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Bibliographic Details
Main Authors: Chinatsu Nishida, Hiroto Izumi, Taisuke Tomonaga, Ke-Yong Wang, Hidenori Higashi, Jun-Ichi Takeshita, Ryohei Ono, Kazuki Sumiya, Shota Fujii, Yuki Hata, Kazuo Sakurai, Yasuyuki Higashi, Kei Yamasaki, Kazuhiro Yatera, Yasuo Morimoto
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Molecular Sciences
Subjects:
polyacrylic acid (PAA)
organic compounds
molecular weight
pulmonary toxicity
Online Access:https://www.mdpi.com/1422-0067/23/18/10345

Internet

https://www.mdpi.com/1422-0067/23/18/10345

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