Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia

Downregulation of lysyl oxidase and lysyl oxidase-like protein 2 suppressed the migration and invasion of trophoblasts by activating the TGF-β/collagen pathway in preeclampsia

Preeclampsia: when cells aren’t invasive enough Cancer-associated proteins play a role in preeclampsia, a potentially life-threatening disorder of pregnancy marked by high blood pressure and protein in the urine. The causes of preeclampsia are poorly understood, but the tissue that nourishes the fet...

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Bibliographic Details
Main Authors: Xiang-Hong Xu, Yuanhui Jia, Xinyao Zhou, Dandan Xie, Xiaojie Huang, Linyan Jia, Qian Zhou, Qingliang Zheng, Xiangyu Zhou, Kai Wang, Li-Ping Jin
Format: Article
Language:English
Published: Nature Publishing Group 2019-02-01
Series:Experimental and Molecular Medicine
Online Access:https://doi.org/10.1038/s12276-019-0211-9

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