Patent trend and competitive analysis of cancer immunotherapy in the United States

Immunotherapy has brought high hopes for cancer treatment, and attracted tremendous resources from the biopharmaceutical community. Here we analyze cancer immunotherapy-related patents granted by the United States Patent and Trademark Office in the past decade (2006–2016). A total of 2,229 patents w...

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Main Authors: Chia-Lin Pan, Feng-Chi Chen
Format: Article
Language:English
Published: Taylor & Francis Group 2017-11-01
Series:Human Vaccines & Immunotherapeutics
Subjects:
Online Access:http://dx.doi.org/10.1080/21645515.2017.1361074
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author Chia-Lin Pan
Feng-Chi Chen
author_facet Chia-Lin Pan
Feng-Chi Chen
author_sort Chia-Lin Pan
collection DOAJ
description Immunotherapy has brought high hopes for cancer treatment, and attracted tremendous resources from the biopharmaceutical community. Here we analyze cancer immunotherapy-related patents granted by the United States Patent and Trademark Office in the past decade (2006–2016). A total of 2,229 patents were identified in 13 subfields. The growth of patent number in this field has outpaced the background rate, with cytokine-related therapies, immune checkpoint inhibitors, and natural killer cell therapies growing the most rapidly. The top 15 assignees possess 27.6% (616) of the patents. Amgen is the largest patent holder, followed by Novartis, and then by Chugai Seiyaku. The top assignees have focused on different subfields, and collaborated with each other for technology development. Our competitive analysis reveals that Novartis, Chugai Seiyaku, and Abbvie lead in both patent number and average quality of patents. Meanwhile, Immunomedics owns a high-quality though relatively small patent portfolio in single-chain variable fragment technology, which is not the focus of the abovementioned forerunners. Overall, our analysis illustrates an ecosystem where industry giants and smaller-size players each occupies a niche. Selection and succession are expected to continue for years in this young ecosystem.
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spelling doaj.art-595940ff752f47f0b542fc3ceba571042023-09-22T08:17:51ZengTaylor & Francis GroupHuman Vaccines & Immunotherapeutics2164-55152164-554X2017-11-0113112583259310.1080/21645515.2017.13610741361074Patent trend and competitive analysis of cancer immunotherapy in the United StatesChia-Lin Pan0Feng-Chi Chen1Institute of Population Health Sciences, National Health Research InstitutesInstitute of Population Health Sciences, National Health Research InstitutesImmunotherapy has brought high hopes for cancer treatment, and attracted tremendous resources from the biopharmaceutical community. Here we analyze cancer immunotherapy-related patents granted by the United States Patent and Trademark Office in the past decade (2006–2016). A total of 2,229 patents were identified in 13 subfields. The growth of patent number in this field has outpaced the background rate, with cytokine-related therapies, immune checkpoint inhibitors, and natural killer cell therapies growing the most rapidly. The top 15 assignees possess 27.6% (616) of the patents. Amgen is the largest patent holder, followed by Novartis, and then by Chugai Seiyaku. The top assignees have focused on different subfields, and collaborated with each other for technology development. Our competitive analysis reveals that Novartis, Chugai Seiyaku, and Abbvie lead in both patent number and average quality of patents. Meanwhile, Immunomedics owns a high-quality though relatively small patent portfolio in single-chain variable fragment technology, which is not the focus of the abovementioned forerunners. Overall, our analysis illustrates an ecosystem where industry giants and smaller-size players each occupies a niche. Selection and succession are expected to continue for years in this young ecosystem.http://dx.doi.org/10.1080/21645515.2017.1361074immunotherapycancerpatent landscapepatent analysiscompetitive analysis
spellingShingle Chia-Lin Pan
Feng-Chi Chen
Patent trend and competitive analysis of cancer immunotherapy in the United States
Human Vaccines & Immunotherapeutics
immunotherapy
cancer
patent landscape
patent analysis
competitive analysis
title Patent trend and competitive analysis of cancer immunotherapy in the United States
title_full Patent trend and competitive analysis of cancer immunotherapy in the United States
title_fullStr Patent trend and competitive analysis of cancer immunotherapy in the United States
title_full_unstemmed Patent trend and competitive analysis of cancer immunotherapy in the United States
title_short Patent trend and competitive analysis of cancer immunotherapy in the United States
title_sort patent trend and competitive analysis of cancer immunotherapy in the united states
topic immunotherapy
cancer
patent landscape
patent analysis
competitive analysis
url http://dx.doi.org/10.1080/21645515.2017.1361074
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