Diversity of breakpoints of variant Philadelphia chromosomes in chronic myeloid leukemia in Brazilian patients
Background: Chronic myeloid leukemia is a myeloproliferative disorder characterized by the Philadelphia chromosome or t(9;22)(q34.1;q11.2), resulting in the break-point cluster regionAbelson tyrosine kinase fusion gene, which encodes a constitutively active tyrosine kinase protein. The Philadelphia...
Huvudupphovsmän: | , , |
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Materialtyp: | Artikel |
Språk: | English |
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Elsevier
2015-02-01
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Serie: | Revista Brasileira de Hematologia e Hemoterapia |
Ämnen: | |
Länkar: | http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-84842015000100017&lng=en&tlng=en |