"Investigating Moderation in the Prospective Relationship of Marijuana Use to Subsequent Illicit Substance Use: Evidence from Add Health

While socially normalized substances (e.g., marijuana) may increase the probability of subsequent progression to more harmful illicit substances, previous empirical research on the topic has yielded inconsistent results. Few studies have prospectively examined whether age of first documented current...

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Main Authors: Radhika Prasad, Ming Wen, Zobayer Ahmmad, Daniel E. Adkins
Format: Article
Language:English
Published: New Prairie Press 2023-08-01
Series:Health Behavior Research
Subjects:
Online Access:https://newprairiepress.org/hbr/vol6/iss2/3/
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author Radhika Prasad
Ming Wen
Zobayer Ahmmad
Daniel E. Adkins
author_facet Radhika Prasad
Ming Wen
Zobayer Ahmmad
Daniel E. Adkins
author_sort Radhika Prasad
collection DOAJ
description While socially normalized substances (e.g., marijuana) may increase the probability of subsequent progression to more harmful illicit substances, previous empirical research on the topic has yielded inconsistent results. Few studies have prospectively examined whether age of first documented current marijuana use is related to later harmful illicit substance use over multiple life course stages, or considered potential moderation of the process by age of first documented current marijuana use, gender, or race/ethnicity. To investigate this topic, data from five waves the National Longitudinal Study of Adolescent to Adult (N=20,774), spanning ages 12-42, were used to analyze the prospective association of current marijuana use at any of the five waves to current illicit substances in early middle adulthood (i.e., Wave 5), conditional on sociodemographic controls. Moderation in the effect of first documented current marijuana use on later illicit substance use was tested for three putative moderators, gender, race/ethnicity, and age of first reported current marijuana use, using interaction effects. Multiple imputation was used to address a modest amount of missing data. Results indicate that current marijuana use at any wave was strongly associated with documented current illicit substance use in middle adulthood (OR = 4.506, p < .001), conditional on socio-demographic controls. Furthermore, individuals whose first documented current marijuana use occurred in young adulthood had lower odds of using more harmful illicit substances in early middle adulthood, compared to those who first reported current marijuana use in adolescence or the transition to adulthood (OR = 0.662, p < .05). There was no evidence of moderation by gender or racial/ethnicity. Our results suggest that individuals who report using marijuana in adolescence and the transition to adulthood have greater likelihood of more harmful illicit substance use in early middle adulthood.
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spelling doaj.art-595e5f0b23524a98993013e27e3568492023-08-11T16:08:34ZengNew Prairie PressHealth Behavior Research2572-18362023-08-016210.4148/2572-1836.1172"Investigating Moderation in the Prospective Relationship of Marijuana Use to Subsequent Illicit Substance Use: Evidence from Add Health Radhika Prasad Ming WenZobayer Ahmmad Daniel E. AdkinsWhile socially normalized substances (e.g., marijuana) may increase the probability of subsequent progression to more harmful illicit substances, previous empirical research on the topic has yielded inconsistent results. Few studies have prospectively examined whether age of first documented current marijuana use is related to later harmful illicit substance use over multiple life course stages, or considered potential moderation of the process by age of first documented current marijuana use, gender, or race/ethnicity. To investigate this topic, data from five waves the National Longitudinal Study of Adolescent to Adult (N=20,774), spanning ages 12-42, were used to analyze the prospective association of current marijuana use at any of the five waves to current illicit substances in early middle adulthood (i.e., Wave 5), conditional on sociodemographic controls. Moderation in the effect of first documented current marijuana use on later illicit substance use was tested for three putative moderators, gender, race/ethnicity, and age of first reported current marijuana use, using interaction effects. Multiple imputation was used to address a modest amount of missing data. Results indicate that current marijuana use at any wave was strongly associated with documented current illicit substance use in middle adulthood (OR = 4.506, p < .001), conditional on socio-demographic controls. Furthermore, individuals whose first documented current marijuana use occurred in young adulthood had lower odds of using more harmful illicit substances in early middle adulthood, compared to those who first reported current marijuana use in adolescence or the transition to adulthood (OR = 0.662, p < .05). There was no evidence of moderation by gender or racial/ethnicity. Our results suggest that individuals who report using marijuana in adolescence and the transition to adulthood have greater likelihood of more harmful illicit substance use in early middle adulthood.https://newprairiepress.org/hbr/vol6/iss2/3/marijuana usecannabis useillicit substance usecohort studylongitudinal data
spellingShingle Radhika Prasad
Ming Wen
Zobayer Ahmmad
Daniel E. Adkins
"Investigating Moderation in the Prospective Relationship of Marijuana Use to Subsequent Illicit Substance Use: Evidence from Add Health
Health Behavior Research
marijuana use
cannabis use
illicit substance use
cohort study
longitudinal data
title "Investigating Moderation in the Prospective Relationship of Marijuana Use to Subsequent Illicit Substance Use: Evidence from Add Health
title_full "Investigating Moderation in the Prospective Relationship of Marijuana Use to Subsequent Illicit Substance Use: Evidence from Add Health
title_fullStr "Investigating Moderation in the Prospective Relationship of Marijuana Use to Subsequent Illicit Substance Use: Evidence from Add Health
title_full_unstemmed "Investigating Moderation in the Prospective Relationship of Marijuana Use to Subsequent Illicit Substance Use: Evidence from Add Health
title_short "Investigating Moderation in the Prospective Relationship of Marijuana Use to Subsequent Illicit Substance Use: Evidence from Add Health
title_sort investigating moderation in the prospective relationship of marijuana use to subsequent illicit substance use evidence from add health
topic marijuana use
cannabis use
illicit substance use
cohort study
longitudinal data
url https://newprairiepress.org/hbr/vol6/iss2/3/
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