Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study
Glycosylated hemoglobin A1c (HbA1c) level has strong relevance to microvascular disorders, which are also thought to be the current main aspect of sudden sensorineural hearing loss (SSNHL), so we aim to elucidate the association of the HbA1c level with the severity, types, and prognosis of SSNHL. In...
| Main Authors: | , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2021-11-01
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| Series: | Frontiers in Endocrinology |
| Subjects: | |
| Online Access: | https://www.frontiersin.org/articles/10.3389/fendo.2021.763021/full |
| _version_ | 1818837011441647616 |
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| author | Ying Shen Ying Shen Zhong Zheng Zhong Zheng Lili Xiao Lili Xiao Chengqi Liu Chengqi Liu Jingyi Guo Zhengnong Chen Zhengnong Chen Yaqin Wu Yaqin Wu Haibo Shi Haibo Shi Zhen Zhang Zhen Zhang Di Qian Yanmei Feng Yanmei Feng Shankai Yin Shankai Yin |
| author_facet | Ying Shen Ying Shen Zhong Zheng Zhong Zheng Lili Xiao Lili Xiao Chengqi Liu Chengqi Liu Jingyi Guo Zhengnong Chen Zhengnong Chen Yaqin Wu Yaqin Wu Haibo Shi Haibo Shi Zhen Zhang Zhen Zhang Di Qian Yanmei Feng Yanmei Feng Shankai Yin Shankai Yin |
| author_sort | Ying Shen |
| collection | DOAJ |
| description | Glycosylated hemoglobin A1c (HbA1c) level has strong relevance to microvascular disorders, which are also thought to be the current main aspect of sudden sensorineural hearing loss (SSNHL), so we aim to elucidate the association of the HbA1c level with the severity, types, and prognosis of SSNHL. In this study, comparative analyses based on propensity score matching of the severity, types, and prognosis of SSNHL with the HbA1c level in 116 patients diagnosed as SSNHL were conducted, where they were divided into diabetes mellitus (DM) group and non-DM group. We finally found that, among patients with SSNHL, diabetic patients had a higher HbA1c level, more severe hearing loss, and poorer prognosis than non-diabetic patients. The HbA1c level was found to be significantly correlated with the severity and types of SSNHL, while no strong relevance was found between the higher HbA1c level and the poorer prognosis of SSNHL. |
| first_indexed | 2024-12-19T03:15:43Z |
| format | Article |
| id | doaj.art-5962e6df7361447b88d9b5fe356a2198 |
| institution | Directory Open Access Journal |
| issn | 1664-2392 |
| language | English |
| last_indexed | 2024-12-19T03:15:43Z |
| publishDate | 2021-11-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Endocrinology |
| spelling | doaj.art-5962e6df7361447b88d9b5fe356a21982022-12-21T20:37:53ZengFrontiers Media S.A.Frontiers in Endocrinology1664-23922021-11-011210.3389/fendo.2021.763021763021Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective StudyYing Shen0Ying Shen1Zhong Zheng2Zhong Zheng3Lili Xiao4Lili Xiao5Chengqi Liu6Chengqi Liu7Jingyi Guo8Zhengnong Chen9Zhengnong Chen10Yaqin Wu11Yaqin Wu12Haibo Shi13Haibo Shi14Zhen Zhang15Zhen Zhang16Di Qian17Yanmei Feng18Yanmei Feng19Shankai Yin20Shankai Yin21Department of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaClinical Research Center, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaDepartment of Otolaryngology, People’s Hospital of Longhua, Shenzhen, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaDepartment of Otolaryngology Head and Neck Surgery, Shanghai Jiao Tong University Affiliated Sixth People’s Hospital, Shanghai, ChinaShanghai Key Laboratory of Sleep Disordered Breathing, Shanghai, ChinaGlycosylated hemoglobin A1c (HbA1c) level has strong relevance to microvascular disorders, which are also thought to be the current main aspect of sudden sensorineural hearing loss (SSNHL), so we aim to elucidate the association of the HbA1c level with the severity, types, and prognosis of SSNHL. In this study, comparative analyses based on propensity score matching of the severity, types, and prognosis of SSNHL with the HbA1c level in 116 patients diagnosed as SSNHL were conducted, where they were divided into diabetes mellitus (DM) group and non-DM group. We finally found that, among patients with SSNHL, diabetic patients had a higher HbA1c level, more severe hearing loss, and poorer prognosis than non-diabetic patients. The HbA1c level was found to be significantly correlated with the severity and types of SSNHL, while no strong relevance was found between the higher HbA1c level and the poorer prognosis of SSNHL.https://www.frontiersin.org/articles/10.3389/fendo.2021.763021/fullsudden sensorineural hearing lossdiabetes mellitusglycosylated hemoglobin A1cmicrovascular disorderspropensity score matching |
| spellingShingle | Ying Shen Ying Shen Zhong Zheng Zhong Zheng Lili Xiao Lili Xiao Chengqi Liu Chengqi Liu Jingyi Guo Zhengnong Chen Zhengnong Chen Yaqin Wu Yaqin Wu Haibo Shi Haibo Shi Zhen Zhang Zhen Zhang Di Qian Yanmei Feng Yanmei Feng Shankai Yin Shankai Yin Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study Frontiers in Endocrinology sudden sensorineural hearing loss diabetes mellitus glycosylated hemoglobin A1c microvascular disorders propensity score matching |
| title | Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study |
| title_full | Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study |
| title_fullStr | Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study |
| title_full_unstemmed | Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study |
| title_short | Association of Glycosylated Hemoglobin A1c Level With Sudden Sensorineural Hearing Loss: A Prospective Study |
| title_sort | association of glycosylated hemoglobin a1c level with sudden sensorineural hearing loss a prospective study |
| topic | sudden sensorineural hearing loss diabetes mellitus glycosylated hemoglobin A1c microvascular disorders propensity score matching |
| url | https://www.frontiersin.org/articles/10.3389/fendo.2021.763021/full |
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