Total Blood Lymphocyte Count Alteration During and after Pregnancy

Objective: To investigate the impact of gestational changes on blood lymphocyte count in healthy pregnancies. Study Design: This retrospective study is consisted of 108 consecutive normal pregnancies who delivered at our department in December 2015. High-risk pregnancies with poor neonatal outcome...

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Main Authors: Gökçen Örgül, Burcu Soyak, Oytun Portakal, Meral Beksaç, M. Sinan Beksaç
Format: Article
Language:English
Published: Medical Network 2017-04-01
Series:Gynecology Obstetrics & Reproductive Medicine
Subjects:
Online Access:http://gorm.com.tr/index.php/GORM/article/view/633
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author Gökçen Örgül
Burcu Soyak
Oytun Portakal
Meral Beksaç
M. Sinan Beksaç
author_facet Gökçen Örgül
Burcu Soyak
Oytun Portakal
Meral Beksaç
M. Sinan Beksaç
author_sort Gökçen Örgül
collection DOAJ
description Objective: To investigate the impact of gestational changes on blood lymphocyte count in healthy pregnancies. Study Design: This retrospective study is consisted of 108 consecutive normal pregnancies who delivered at our department in December 2015. High-risk pregnancies with poor neonatal outcome and pregnancies with maternal disorders which may affect lymphocyte counts were excluded from the study. “Complete blood count” results of the patients were obtained from the computerized data base system of Hacettepe University Hospital. Blood samples of patients which were withdrawn a) prior to pregnancy (1-6 months before getting pregnant), b) during pregnancy (11-14th gestational weeks) and c) post-partum first day were used in this study. Results: The mean blood lymphocyte count was 2049.07 (±758.69) in patients before their pregnancies. The mean lymphocyte count decreased to 1850.93 and 1625 during pregnancy and after delivery respectively. A statistically significant decrease was found between three periods (before, during, and postpartum 1st day) (p:0.003). Conclusion: We have shown a significant decrease in total lymphocyte levels during pregnancy, consistent with the data presented in the literature. Pregnancy and related hormones have a negative impact on total blood lymphocyte level.
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spelling doaj.art-596a2e4e32184760b26d5dbcb510d68a2023-02-15T16:19:47ZengMedical NetworkGynecology Obstetrics & Reproductive Medicine1300-47512017-04-01231111310.21613/GORM.2016.633557Total Blood Lymphocyte Count Alteration During and after PregnancyGökçen ÖrgülBurcu SoyakOytun PortakalMeral BeksaçM. Sinan BeksaçObjective: To investigate the impact of gestational changes on blood lymphocyte count in healthy pregnancies. Study Design: This retrospective study is consisted of 108 consecutive normal pregnancies who delivered at our department in December 2015. High-risk pregnancies with poor neonatal outcome and pregnancies with maternal disorders which may affect lymphocyte counts were excluded from the study. “Complete blood count” results of the patients were obtained from the computerized data base system of Hacettepe University Hospital. Blood samples of patients which were withdrawn a) prior to pregnancy (1-6 months before getting pregnant), b) during pregnancy (11-14th gestational weeks) and c) post-partum first day were used in this study. Results: The mean blood lymphocyte count was 2049.07 (±758.69) in patients before their pregnancies. The mean lymphocyte count decreased to 1850.93 and 1625 during pregnancy and after delivery respectively. A statistically significant decrease was found between three periods (before, during, and postpartum 1st day) (p:0.003). Conclusion: We have shown a significant decrease in total lymphocyte levels during pregnancy, consistent with the data presented in the literature. Pregnancy and related hormones have a negative impact on total blood lymphocyte level.http://gorm.com.tr/index.php/GORM/article/view/633Pregnancy, Lymphocyte count, Hematocrit
spellingShingle Gökçen Örgül
Burcu Soyak
Oytun Portakal
Meral Beksaç
M. Sinan Beksaç
Total Blood Lymphocyte Count Alteration During and after Pregnancy
Gynecology Obstetrics & Reproductive Medicine
Pregnancy, Lymphocyte count, Hematocrit
title Total Blood Lymphocyte Count Alteration During and after Pregnancy
title_full Total Blood Lymphocyte Count Alteration During and after Pregnancy
title_fullStr Total Blood Lymphocyte Count Alteration During and after Pregnancy
title_full_unstemmed Total Blood Lymphocyte Count Alteration During and after Pregnancy
title_short Total Blood Lymphocyte Count Alteration During and after Pregnancy
title_sort total blood lymphocyte count alteration during and after pregnancy
topic Pregnancy, Lymphocyte count, Hematocrit
url http://gorm.com.tr/index.php/GORM/article/view/633
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AT oytunportakal totalbloodlymphocytecountalterationduringandafterpregnancy
AT meralbeksac totalbloodlymphocytecountalterationduringandafterpregnancy
AT msinanbeksac totalbloodlymphocytecountalterationduringandafterpregnancy