ATORVASTATIN IN ACUTE AND CHRONIC KINDS OF ISCHEMIC HEART DISEASE

The review focuses on clinical trials data demonstrating a possibility of effective statin therapy of acute and chronic ischemic heart disease courses. The analysis of maximal dosages of atorvastatin application provided, its early prescription in first 24-96 hours after acute cardiovascular event a...

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Main Authors: V. E. Oleynikov, A. A. Khromova, L. I. Gusakovskaya, N. V. Sergatskaya, E. M. Romanovskaya
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2015-11-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/463
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author V. E. Oleynikov
A. A. Khromova
L. I. Gusakovskaya
N. V. Sergatskaya
E. M. Romanovskaya
author_facet V. E. Oleynikov
A. A. Khromova
L. I. Gusakovskaya
N. V. Sergatskaya
E. M. Romanovskaya
author_sort V. E. Oleynikov
collection DOAJ
description The review focuses on clinical trials data demonstrating a possibility of effective statin therapy of acute and chronic ischemic heart disease courses. The analysis of maximal dosages of atorvastatin application provided, its early prescription in first 24-96 hours after acute cardiovascular event and in preparing for revascularization with the aim to minimize the risk of adverse effects, death and to improve prognosis. The positive effect of atorvastatin is taken into consideration, mediated by not only its hypolipidemic effect, but a range of pleiotropic effects. The analysis is provided of the data on prevalence and severity of side effects in patients receiving statins.
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spelling doaj.art-596a8d9cecf4460abe1f8ca50a7732392023-03-29T21:23:24Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202015-11-010119810310.15829/1560-4071-2015-11-98-103463ATORVASTATIN IN ACUTE AND CHRONIC KINDS OF ISCHEMIC HEART DISEASEV. E. Oleynikov0A. A. Khromova1L. I. Gusakovskaya2N. V. Sergatskaya3E. M. Romanovskaya4ФГБОУ ВПО Пензенский государственный университет, медицинский институт, Пенза, РоссияFSBEI HPE Penza State University, Medical Institute, Penza, RussiaFSBEI HPE Penza State University, Medical Institute, Penza, RussiaFSBEI HPE Penza State University, Medical Institute, Penza, RussiaFSBEI HPE Penza State University, Medical Institute, Penza, RussiaThe review focuses on clinical trials data demonstrating a possibility of effective statin therapy of acute and chronic ischemic heart disease courses. The analysis of maximal dosages of atorvastatin application provided, its early prescription in first 24-96 hours after acute cardiovascular event and in preparing for revascularization with the aim to minimize the risk of adverse effects, death and to improve prognosis. The positive effect of atorvastatin is taken into consideration, mediated by not only its hypolipidemic effect, but a range of pleiotropic effects. The analysis is provided of the data on prevalence and severity of side effects in patients receiving statins.https://russjcardiol.elpub.ru/jour/article/view/463chdatorvastatinstatinspleiotropic effectside effects.
spellingShingle V. E. Oleynikov
A. A. Khromova
L. I. Gusakovskaya
N. V. Sergatskaya
E. M. Romanovskaya
ATORVASTATIN IN ACUTE AND CHRONIC KINDS OF ISCHEMIC HEART DISEASE
Российский кардиологический журнал
chd
atorvastatin
statins
pleiotropic effect
side effects.
title ATORVASTATIN IN ACUTE AND CHRONIC KINDS OF ISCHEMIC HEART DISEASE
title_full ATORVASTATIN IN ACUTE AND CHRONIC KINDS OF ISCHEMIC HEART DISEASE
title_fullStr ATORVASTATIN IN ACUTE AND CHRONIC KINDS OF ISCHEMIC HEART DISEASE
title_full_unstemmed ATORVASTATIN IN ACUTE AND CHRONIC KINDS OF ISCHEMIC HEART DISEASE
title_short ATORVASTATIN IN ACUTE AND CHRONIC KINDS OF ISCHEMIC HEART DISEASE
title_sort atorvastatin in acute and chronic kinds of ischemic heart disease
topic chd
atorvastatin
statins
pleiotropic effect
side effects.
url https://russjcardiol.elpub.ru/jour/article/view/463
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AT aakhromova atorvastatininacuteandchronickindsofischemicheartdisease
AT ligusakovskaya atorvastatininacuteandchronickindsofischemicheartdisease
AT nvsergatskaya atorvastatininacuteandchronickindsofischemicheartdisease
AT emromanovskaya atorvastatininacuteandchronickindsofischemicheartdisease