Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria
Abstract Podocytes are specialized epithelial cells that play a significant role in maintaining the integrity of the glomerular filtration barrier and preventing urinary protein leakage. We investigated the contribution of protein tyrosine phosphatase Shp2 to lipopolysaccharide (LPS)-induced renal i...
Main Authors: | Ming-Fo Hsu, Ahmed Bettaieb, Yoshihiro Ito, James Graham, Peter J. Havel, Fawaz G. Haj |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2017-03-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-017-00564-3 |
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