Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review

Cerebrovascular accident (CVA) in patients with various cardiovascular diseases is a life-threatening complication, the development of which can be contributed by both environmental and genetic factors, the understanding of which is necessary to determine the tactics of treatment and predict the dis...

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Main Authors: A. A. Chernova, D. A. Nikulin, S. Yu. Nikulina, V. N. Maksimov
Format: Article
Language:Russian
Published: «FIRMA «SILICEA» LLC 2022-11-01
Series:Российский кардиологический журнал
Subjects:
Online Access:https://russjcardiol.elpub.ru/jour/article/view/5127
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author A. A. Chernova
D. A. Nikulin
S. Yu. Nikulina
V. N. Maksimov
author_facet A. A. Chernova
D. A. Nikulin
S. Yu. Nikulina
V. N. Maksimov
author_sort A. A. Chernova
collection DOAJ
description Cerebrovascular accident (CVA) in patients with various cardiovascular diseases is a life-threatening complication, the development of which can be contributed by both environmental and genetic factors, the understanding of which is necessary to determine the tactics of treatment and predict the disease course. The article presents a brief review of studies on genetic predictors of CVA, in particular the association of the ABCA1 rs2230806 polymorphism and the risk of CVA in cardiovascular patients. Targeted studies of associations of the ABCA1 rs2230806 polymorphism with cerebrovascular diseases in the Russian Federation, except for studies at our university, could not be found.
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spelling doaj.art-596fc916676948e7be8882f4bef3a9c82023-03-29T21:23:41Zrus«FIRMA «SILICEA» LLCРоссийский кардиологический журнал1560-40712618-76202022-11-01271010.15829/1560-4071-2022-51273621Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature reviewA. A. Chernova0D. A. Nikulin1S. Yu. Nikulina2V. N. Maksimov3V.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Federal Siberian Research Clinical CenterV.F. Voyno-Yasenetsky Krasnoyarsk State Medical University; Federal Siberian Research Clinical CenterV.F. Voyno-Yasenetsky Krasnoyarsk State Medical UniversityResearch Institute of Internal and Preventive Medicine — a branch of the Federal Research Center Institute of Cytology and GeneticsCerebrovascular accident (CVA) in patients with various cardiovascular diseases is a life-threatening complication, the development of which can be contributed by both environmental and genetic factors, the understanding of which is necessary to determine the tactics of treatment and predict the disease course. The article presents a brief review of studies on genetic predictors of CVA, in particular the association of the ABCA1 rs2230806 polymorphism and the risk of CVA in cardiovascular patients. Targeted studies of associations of the ABCA1 rs2230806 polymorphism with cerebrovascular diseases in the Russian Federation, except for studies at our university, could not be found.https://russjcardiol.elpub.ru/jour/article/view/5127cerebrovascular accidentgenetic markerssnpchromosome 9cardiovascular diseases
spellingShingle A. A. Chernova
D. A. Nikulin
S. Yu. Nikulina
V. N. Maksimov
Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review
Российский кардиологический журнал
cerebrovascular accident
genetic markers
snp
chromosome 9
cardiovascular diseases
title Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review
title_full Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review
title_fullStr Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review
title_full_unstemmed Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review
title_short Pleiotropic effect of the ABCA1 rs2230806 polymorphism in cardiovascular diseases: a literature review
title_sort pleiotropic effect of the abca1 rs2230806 polymorphism in cardiovascular diseases a literature review
topic cerebrovascular accident
genetic markers
snp
chromosome 9
cardiovascular diseases
url https://russjcardiol.elpub.ru/jour/article/view/5127
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AT syunikulina pleiotropiceffectoftheabca1rs2230806polymorphismincardiovasculardiseasesaliteraturereview
AT vnmaksimov pleiotropiceffectoftheabca1rs2230806polymorphismincardiovasculardiseasesaliteraturereview