Role of first trimester uterine artery Doppler indices in Prediction of pre-eclampsia
Background: Pre-eclampsia (PE) is associated with a high rate of maternal and perinatal morbidity and mortality, so its prediction has a tremendous impact on its management. Objectives: To evaluate the role of uterine artery Doppler indices in the prediction of pre-eclampsia during the first trimes...
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| Format: | Article |
| Language: | English |
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South Valley University, Faculty of Medicine
2024-01-01
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| Series: | SVU - International Journal of Medical Sciences |
| Subjects: | |
| Online Access: | https://svuijm.journals.ekb.eg/article_340677.html |
| _version_ | 1797255787609849856 |
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| author | Mostafa Mohamed Khodary Ahmed Hashim Abdel Ellah Suma Abdelraheem Abouelwafa* Mahmoud Souliman Iwes |
| author_facet | Mostafa Mohamed Khodary Ahmed Hashim Abdel Ellah Suma Abdelraheem Abouelwafa* Mahmoud Souliman Iwes |
| author_sort | Mostafa Mohamed Khodary |
| collection | DOAJ |
| description | Background: Pre-eclampsia (PE) is associated with a high rate of maternal and perinatal morbidity and mortality, so its prediction has a tremendous impact on its management.
Objectives: To evaluate the role of uterine artery Doppler indices in the prediction of pre-eclampsia during the first trimester of pregnancy.
Patients and methods: During the early stages of their pregnancies, 60 expectant mothers received early pregnancy care at South Valley University Hospital between weeks 9 and 11. Assessments included clinical exams, medical history, lab tests, abdominal ultrasound, and uterine artery Doppler scans at 9, 11, and 18 weeks.
Results: The mean age of patients was 24.8 ± 3.4 years, with a mean body mass index (BMI) of 24 ± 2.3 kg/m2. There were 13 patients (23.6%) with PE; out of them, 9 patients had a severe form of PE, and 42 patients (76.4%) had no PE. Doppler flow study of the uterine artery at 9–11 and 18 weeks showed statistically significant (p-value<0.05) increased left and right uterine artery pulsatility index (PI) and residence index (RI) in patients with PE (1.17±0.33) when compared with patients without PE (0.95±0.28), and there was a highly statistically significant (p-value<0.05) increased percentage of presence of notch in patients with PE (7 patients, 53.8%) when compared with patients without PE.
Conclusion: We found statistically significant increases in uterine artery PI and RI in patients with PE when compared with patients without PE. The presence of notch in the uterine artery wave is highly predictive for development of preeclampsia. |
| first_indexed | 2024-04-24T22:11:24Z |
| format | Article |
| id | doaj.art-59716a54b5fa41ef8783d5075caddb53 |
| institution | Directory Open Access Journal |
| issn | 2735-427X 2636-3402 |
| language | English |
| last_indexed | 2024-04-24T22:11:24Z |
| publishDate | 2024-01-01 |
| publisher | South Valley University, Faculty of Medicine |
| record_format | Article |
| series | SVU - International Journal of Medical Sciences |
| spelling | doaj.art-59716a54b5fa41ef8783d5075caddb532024-03-20T08:43:08ZengSouth Valley University, Faculty of MedicineSVU - International Journal of Medical Sciences2735-427X2636-34022024-01-0171304316https://doi.org/10.21608/svuijm.2023.236407.1698Role of first trimester uterine artery Doppler indices in Prediction of pre-eclampsiaMostafa Mohamed Khodary 0Ahmed Hashim Abdel Ellah 1Suma Abdelraheem Abouelwafa*2Mahmoud Souliman Iwes3Obstetrics and Gynecology Department, Faculty of Medicine, South Valley University, Qena, EgyptObstetrics and Gynecology Department, Faculty of Medicine, South Valley University, Qena, EgyptObstetrics and Gynecology Department, Faculty of Medicine, South Valley University, Qena, EgyptObstetrics and Gynecology Department, Faculty of Medicine, South Valley University, Qena, EgyptBackground: Pre-eclampsia (PE) is associated with a high rate of maternal and perinatal morbidity and mortality, so its prediction has a tremendous impact on its management. Objectives: To evaluate the role of uterine artery Doppler indices in the prediction of pre-eclampsia during the first trimester of pregnancy. Patients and methods: During the early stages of their pregnancies, 60 expectant mothers received early pregnancy care at South Valley University Hospital between weeks 9 and 11. Assessments included clinical exams, medical history, lab tests, abdominal ultrasound, and uterine artery Doppler scans at 9, 11, and 18 weeks. Results: The mean age of patients was 24.8 ± 3.4 years, with a mean body mass index (BMI) of 24 ± 2.3 kg/m2. There were 13 patients (23.6%) with PE; out of them, 9 patients had a severe form of PE, and 42 patients (76.4%) had no PE. Doppler flow study of the uterine artery at 9–11 and 18 weeks showed statistically significant (p-value<0.05) increased left and right uterine artery pulsatility index (PI) and residence index (RI) in patients with PE (1.17±0.33) when compared with patients without PE (0.95±0.28), and there was a highly statistically significant (p-value<0.05) increased percentage of presence of notch in patients with PE (7 patients, 53.8%) when compared with patients without PE. Conclusion: We found statistically significant increases in uterine artery PI and RI in patients with PE when compared with patients without PE. The presence of notch in the uterine artery wave is highly predictive for development of preeclampsia.https://svuijm.journals.ekb.eg/article_340677.htmluterine artery doppler pre-eclampsia pregnancy |
| spellingShingle | Mostafa Mohamed Khodary Ahmed Hashim Abdel Ellah Suma Abdelraheem Abouelwafa* Mahmoud Souliman Iwes Role of first trimester uterine artery Doppler indices in Prediction of pre-eclampsia SVU - International Journal of Medical Sciences uterine artery doppler pre-eclampsia pregnancy |
| title | Role of first trimester uterine artery Doppler indices in Prediction of pre-eclampsia |
| title_full | Role of first trimester uterine artery Doppler indices in Prediction of pre-eclampsia |
| title_fullStr | Role of first trimester uterine artery Doppler indices in Prediction of pre-eclampsia |
| title_full_unstemmed | Role of first trimester uterine artery Doppler indices in Prediction of pre-eclampsia |
| title_short | Role of first trimester uterine artery Doppler indices in Prediction of pre-eclampsia |
| title_sort | role of first trimester uterine artery doppler indices in prediction of pre eclampsia |
| topic | uterine artery doppler pre-eclampsia pregnancy |
| url | https://svuijm.journals.ekb.eg/article_340677.html |
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